在中国个体中使用基于聚合酶链反应序列分型法鉴定一个新的HLA-A*02等位基因，即HLA-A*02:230。
Identification of a new HLA-A*02 allele, HLA-A*02:230, using polymerase chain reaction sequence-based typing in a Chinese individual.
作者信息
Zhu F-M, He Y-M, Lv H-J, Yan L-X
机构信息
HLA typing laboratory, Blood Center of Zhejiang Province, Hangzhou, Zhejiang Province, China.
出版信息
Tissue Antigens. 2011 Feb;77(2):150-1. doi: 10.1111/j.1399-0039.2010.01573.x. Epub 2010 Oct 12.
Abstract
Nucleotide sequence of HLA-A02:230 allele was different from that of HLA-A02:03:01 by a single nucleotide substitution at codon 139 (GCA > ACA), resulting in one amino acid change (Ala to Thr).
摘要
HLA - A02:230等位基因的核苷酸序列与HLA - A02:03:01的核苷酸序列在第139密码子处存在一个单核苷酸替换（GCA > ACA），导致一个氨基酸变化（丙氨酸变为苏氨酸）。
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