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流产相关严重急性产妇发病率:系统评价。

Incidence of severe acute maternal morbidity associated with abortion: a systematic review.

机构信息

London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Trop Med Int Health. 2012 Feb;17(2):177-90. doi: 10.1111/j.1365-3156.2011.02896.x. Epub 2011 Oct 31.

Abstract

OBJECTIVE

To systematically review articles describing complications of abortion in settings where abortions are thought to be unsafe and to determine the incidence of severe acute maternal morbidity (SAMM) attributed to abortion at the population level.

METHODS

We searched relevant databases using search terms related to abortion and complications. We included population-representative studies that listed complications of abortion. We extracted data on the definitions and numbers of severe complications and SAMM, and we report abortion complication rates (per 100 000 women of reproductive age) and ratios (per 100 000 live births) for SAMM, severe complications and any complications.

RESULTS

We included 15 studies representing eleven countries (six in Africa, four in Asia and one in Latin America). We found a median abortion ratio of SAMM of 237 (range 91-1892) per 100 000 live births and a median abortion ratio of severe complications of 596 (range 435-5298). There was a great degree of heterogeneity between definitions and study populations.

CONCLUSIONS

The burden of SAMM attributed to abortion is much greater than what is reported for deaths caused by abortion. However, the great heterogeneity in definitions makes it difficult to draw firm conclusions. We call for future work on the burden of unsafe abortion to use strict definitions of SAMM.

摘要

目的

系统综述不安全堕胎环境下描述堕胎并发症的文章,并确定人群层面归因于堕胎的严重急性产妇发病率(SAMM)的发生率。

方法

我们使用与堕胎和并发症相关的搜索词搜索了相关数据库。我们纳入了列出堕胎并发症的具有代表性的人群研究。我们提取了严重并发症和 SAMM 的定义和数量数据,并报告了 SAMM、严重并发症和任何并发症的堕胎并发症发生率(每 10 万名育龄妇女)和比值(每 10 万活产)。

结果

我们纳入了来自 11 个国家(6 个非洲国家、4 个亚洲国家和 1 个拉丁美洲国家)的 15 项研究。我们发现,SAMM 的堕胎比值中位数为 237(范围 91-1892)/每 10 万活产,严重并发症的堕胎比值中位数为 596(范围 435-5298)。定义和研究人群之间存在很大的异质性。

结论

归因于堕胎的 SAMM 负担远远大于因堕胎导致的死亡报告。然而,定义上的巨大异质性使得难以得出明确的结论。我们呼吁未来对不安全堕胎负担的研究使用严格的 SAMM 定义。

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