一种与肌营养不良蛋白相关的常染色体基因在人类中定位于6q24，在小鼠中定位于肌营养不良症（dy）基因座所在的10号染色体区域。
Localisation of a dystrophin-related autosomal gene to 6q24 in man, and to mouse chromosome 10 in the region of the dystrophia muscularis (dy) locus.
作者信息
Buckle V J, Guenet J L, Simon-Chazottes D, Love D R, Davies K E
机构信息
Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, UK.
出版信息
Hum Genet. 1990 Aug;85(3):324-6. doi: 10.1007/BF00206755.
We have localised a dystrophin-related autosomal gene called DMDL (Duchenne muscular dystrophy-like) to human chromosome 61q24 by in situ hybridisation. Using restriction fragment length polymorphism analysis in two mouse species, we have localised the homologous gene Dmdl in the mouse to chromosome 10 proximal to the Myb oncogene. A neuromuscular disease locus dystrophia muscularis (dy) has previously been assigned to this region of mouse chromosome 10.
我们通过原位杂交将一个与抗肌萎缩蛋白相关的常染色体基因DMDL（杜氏肌营养不良样）定位于人类61q24染色体。利用两种小鼠物种的限制性片段长度多态性分析，我们已将小鼠中的同源基因Dmdl定位于靠近Myb致癌基因的10号染色体。一种神经肌肉疾病位点肌营养不良（dy）先前已被定位于小鼠10号染色体的这一区域。
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