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使用与安定相当的合适等效剂量进行交叉滴定来对大剂量唑吡坦进行解毒。

Detoxification of high-dose zolpidem using cross-titration with an adequate equivalent dose of diazepam.

机构信息

Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Gen Hosp Psychiatry. 2012 Mar-Apr;34(2):210.e5-7. doi: 10.1016/j.genhosppsych.2011.09.012. Epub 2011 Oct 28.

DOI:10.1016/j.genhosppsych.2011.09.012
PMID:22036737
Abstract

BACKGROUND

There have been numerous case reports of zolpidem abuse and dependence in the recent decade, giving rise to a focus on adverse withdrawal events such as seizure. No standard detoxification regimen has been proposed to date, despite the similarity of effects of zolpidem and benzodiazepines at high doses.

CASE DESCRIPTIONS

We describe the results, in a 53-year-old female patient, of undergoing three different zolpidem detoxification programs.

CONCLUSIONS

Because of her experiences, we recommend using the cross-titration strategy with an adequate equivalent dose of diazepam.

摘要

背景

在最近十年中,有大量佐匹克隆滥用和依赖的病例报告,这引起了人们对戒断时不良反应事件(如癫痫发作)的关注。尽管高剂量的佐匹克隆和苯二氮䓬类药物具有相似的作用,但迄今为止尚未提出标准的戒毒方案。

病例描述

我们描述了一位 53 岁女性患者在接受三种不同的佐匹克隆戒毒方案后的结果。

结论

由于她的经历,我们建议使用交叉滴定策略,使用适当等效剂量的地西泮。

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Detoxification of high-dose zolpidem using cross-titration with an adequate equivalent dose of diazepam.使用与安定相当的合适等效剂量进行交叉滴定来对大剂量唑吡坦进行解毒。
Gen Hosp Psychiatry. 2012 Mar-Apr;34(2):210.e5-7. doi: 10.1016/j.genhosppsych.2011.09.012. Epub 2011 Oct 28.
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