Mitskevich M S
Ontogenez. 1990 May-Jun;21(3):242-53.
Published and author's data on hypothalamic control over the most important endocrine functions during mammalian ontogenesis were reviewed. The data presented indicates that adenohypophyseotropic protein neurohormones are synthesized and accumulated in hypothalamus long before birth. At the end of the prenatal period most of hypothalamic neurohormones reached the adenohypophysis and were involved in regulation of the tropic hormones secretion. Exceptionally, regulative properties of thyroliberin and somatostatin are only manifested in immature-born animals (rats) in early postnatal period.
回顾了已发表的以及作者本人关于哺乳动物个体发育过程中下丘脑对最重要内分泌功能的控制的数据。所呈现的数据表明，腺垂体促激素蛋白神经激素早在出生前就在下丘脑合成并积累。在产前期末，大多数下丘脑神经激素到达腺垂体并参与调节促激素的分泌。例外的是，促甲状腺素释放激素和生长抑素的调节特性仅在出生时不成熟的动物（大鼠）出生后的早期表现出来。
