Cuban Multiple Sclerosis Society, Havana, Cuba.
Eur J Neurol. 2012 Jun;19(6):812-9. doi: 10.1111/j.1468-1331.2011.03565.x. Epub 2011 Oct 31.
Numerous case series have demonstrated that lesions on brain MRI are common in neuromyelitis optica (NMO), but there has not been an attempt to survey and synthesize the literature on neuro-radiology of brain findings in NMO.
To review the studies on conventional brain MRI in NMO and to propose to incorporate characteristic brain MRI lesions into the diagnostic criteria of NMO.
We searched for articles with descriptions of brain MRI findings in NMO in EBSCO, EMBASE, PubMed/Medline, Science Citation Index, and SCOPUS.
Brain abnormalities are seen in majority of NMO patients as disease duration increases. A minority of NMO patients meet Barkhof criteria for space dissemination in multiple sclerosis (MS), and these criteria should not be used to exclude NMO diagnosis. Distinctive brain lesions of NMO are cataloged and described.
Brain lesions in NMO are a consistent feature of the disease. International consensus MRI criteria are needed for NMO analogous to the existing criteria for MS.
大量病例系列研究表明，视神经脊髓炎（NMO）患者的脑 MRI 常有病变，但尚未对 NMO 的神经影像学脑发现进行调查和综合文献的尝试。
回顾 NMO 的常规脑 MRI 研究，并提出将特征性脑 MRI 病变纳入 NMO 的诊断标准。
我们在 EBSCO、EMBASE、PubMed/Medline、科学引文索引和 SCOPUS 中搜索了描述 NMO 脑 MRI 发现的文章。
随着疾病病程的延长，大多数 NMO 患者的脑部异常。少数 NMO 患者符合多发性硬化症（MS）的 Barkhof 空间扩散标准，不应使用这些标准排除 NMO 的诊断。NMO 的独特脑病变被分类和描述。
NMO 的脑病变是该疾病的一个固有特征。需要为 NMO 制定类似于现有 MS 标准的国际共识 MRI 标准。
