Unit of Upgrading of Fishery and Aquaculture Products (U-VPPA), Portuguese Institute of Sea and Fisheries Research (IPIMAR), National Institute of Biological Resources (INRB), Lisbon, Portugal.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(1):94-103. doi: 10.1080/19440049.2011.623284. Epub 2011 Oct 31.
The intake of methyl-mercury (methyl-Hg) through the consumption of three common cephalopod species, cuttlefish (Sepia officinalis), squid (Loligo vulgaris) and octopus (Octopus vulgaris), in Portugal as well as the associated probability of exceeding the provisional tolerable weekly intake (PTWI) were estimated by combining methyl-Hg contamination levels in these three cephalopods with constructed consumption scenarios and with a hypothesised consumption distribution for the general Portuguese population. It was found that squid presents no serious health concern with respect to methyl-Hg, but cuttlefish and octopus consumption should not exceed two 150 g meals per week. Moreover, the methyl-Hg risk assessment for Portuguese consumers showed no risk concerning the observed cephalopods consumption levels. However, besides methyl-Hg, other toxic metals present in cephalopods, such as cadmium, may be a serious health concern and the methyl-Hg risk can be compounded by the risk of other foods containing significant methyl-Hg levels, especially long-lived sea predators. Accordingly, a cautionary note must be attached to advised maximum consumptions, which may be revised by future studies. Tail estimation (TE) estimator was more accurate for lower probabilities, rendering accurate risk estimations different from zero. However, for higher probabilities, the much simpler plug-in (PI) estimator could be applied. Additionally, limitations of a deterministic approach were identified.
通过结合三种常见头足类动物（乌贼、鱿鱼和章鱼）中的甲基汞（甲基-Hg）污染水平与构建的消费情景以及假设的葡萄牙普通人群消费分布，估算了葡萄牙人通过食用这三种头足类动物摄入甲基-Hg 的情况，以及超过暂定可耐受每周摄入量（PTWI）的可能性。研究发现，鱿鱼中的甲基-Hg 不会对健康造成严重威胁，但食用乌贼和章鱼每周不应超过两份 150 克的餐食。此外，葡萄牙消费者的甲基-Hg 风险评估显示，观察到头足类动物的消费水平不存在风险。然而，除了甲基-Hg 之外，头足类动物中存在的其他有毒金属，如镉，可能是一个严重的健康问题，而甲基-Hg 风险可能会因其他含有大量甲基-Hg 水平的食物而加剧，尤其是长寿的海洋捕食者。因此，必须对建议的最大消费额保持警惕，未来的研究可能会对此进行修订。尾估计（TE）估计器在较低概率下更准确，从而对零风险的准确估计与实际情况不同。然而，对于较高的概率，可以应用更简单的插补（PI）估计器。此外，还确定了确定性方法的局限性。
