Khan Muhib, Sidiropoulos Christos, Mitsias Panayiotis
Department of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI, USA.
J Med Case Rep. 2011 Oct 31;5:535. doi: 10.1186/1752-1947-5-535.
Vertical gaze palsy is a recognized manifestation of midbrain lesions. It rarely is a consequence of unilateral thalamic infarction.
We report the case of a 48-year-old African-American woman who presented to our facility with vertical gaze palsy and evidence of left medial thalamic infarct on diffusion-weighted imaging without coexisting midbrain ischemia. The etiology of infarct was determined to be small vessel disease after extensive investigation.
This report suggests a possible role of the thalamus as a vertical gaze control center. Clinicoradiological studies are needed to further define the role of the thalamus in vertical gaze control.
垂直凝视麻痹是中脑病变的一种公认表现。它很少是单侧丘脑梗死的后果。
我们报告了一名48岁非裔美国女性的病例,她因垂直凝视麻痹就诊于我院,弥散加权成像显示左侧内侧丘脑梗死,且不存在中脑缺血。经过广泛检查,梗死病因确定为小血管疾病。
本报告提示丘脑可能作为垂直凝视控制中心发挥作用。需要进行临床影像学研究以进一步明确丘脑在垂直凝视控制中的作用。