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[二极管激光光凝治疗早产儿视网膜病变]

[Diode laser photocoagulation of retinopathy of prematurity].

作者信息

Galván Ledesma A, Morales Guillén C, Pastor Ramos M T, Vázquez Marouschek M del Carmen

机构信息

Servicio de Oftalmología, Hospital Virgen del Rocío, Sevilla, España.

出版信息

Arch Soc Esp Oftalmol. 2011 Nov;86(11):368-73. doi: 10.1016/j.oftal.2011.04.010. Epub 2011 Oct 1.

Abstract

OBJECTIVE

To describe diode laser photocoagulation results in retinopathy of prematurity (ROP) in our hospital.

MATERIAL AND METHOD

Retrospective cross-sectional study based on clinical histories of the premature infants treated during the period from 2004 to 2008.

RESULTS

In the treated group we found a predominance of pre-threshold retinopathy versus threshold retinopathy (84.35% vs 15.65%). The anatomic results were good in 96.5% of 147 eyes. None of the treated eyes in pre-threshold stage showed a poor result. Nine months after treatment, 84.85% of 132 eyes showed good functional results. A poor visual response was associated in most of the cases with neurological diseases. Infants with intraventricular haemorrhages had the worst anatomical and functional results. Strabismus (23.5%) and nystagmus (10.3%) rates were high, probably due to the increased prevalence of neurological diseases. The mortality rate in treated children was 7.3%.

CONCLUSIONS

Diode laser photocoagulation in ROP offers very good anatomical results when performed at the appropriate time. Nevertheless, prematurity is still a very important cause of visual dysfunction in infancy due to the associated neurological disturbances.

摘要

目的

描述我院二极管激光光凝治疗早产儿视网膜病变(ROP)的结果。

材料与方法

基于2004年至2008年期间接受治疗的早产儿临床病史进行回顾性横断面研究。

结果

在治疗组中,我们发现阈值前视网膜病变多于阈值性视网膜病变(84.35%对15.65%)。147只眼中96.5%的解剖结果良好。阈值前阶段的治疗眼均未出现不良结果。治疗9个月后,132只眼中84.85%的功能结果良好。大多数情况下,视觉反应不佳与神经疾病有关。脑室内出血的婴儿解剖和功能结果最差。斜视(23.5%)和眼球震颤(10.3%)发生率较高,可能是由于神经疾病患病率增加所致。治疗儿童的死亡率为7.3%。

结论

在适当的时候进行二极管激光光凝治疗ROP可获得非常好的解剖结果。然而,由于相关的神经功能障碍,早产仍然是婴儿期视力障碍的一个非常重要的原因。

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