Graduate School of Systemic Neurosciences, Ludwig-Maximilians-University, Munich, Germany.
Behav Brain Res. 2012 Feb 1;227(1):21-9. doi: 10.1016/j.bbr.2011.09.042. Epub 2011 Oct 23.
While moving through the world, humans as well as animals can make use of motion cues during both active and passive whole-body motion to track their own position in space. However, the functional neuroanatomy of self-motion processing remains poorly understood. In the present study we aimed to characterize brain networks reflecting whole-body self-motion experience. We used retrieval of previously experienced events, which is known to involve cortical representations of the modalities used to perceive these events. Recollection of self-motion experience may thus engage motor and sensory brain areas, reflecting the active or passive nature of the experienced movement, but may engage also common brain areas processing self-motion. We further compared the retrieval networks of self- and observed motion: even though actual action observation has been shown to recruit brain networks similar to those active during mental simulation, it is unclear to which extent recollection networks of these experiences overlap. Brain activation patterns were recorded using fMRI during mental simulation of recent episodes of (1) experiencing linear whole-body motion (active locomotion and passive transport) and (2) observing another person performing the same tasks. Following the experiential phase, participants recalled the episodes during a MR session. We found that primary sensorimotor brain areas dominate the composition of the recollection network of active walking, while recalling passive transport recruits higher level association areas. Common to both self-motion conditions was activation in the medial temporal lobe. Recollection of self-experienced and observed movement overlapped in motor planning areas. Our results provide evidence that the medial temporal lobe is specifically relevant for retrieval of self-motion information and that motor coding during action observation is reflected in recollection networks.
当人类和动物在主动或被动的全身运动中穿越世界时，它们都可以利用运动线索来跟踪自己在空间中的位置。然而，自我运动处理的功能神经解剖学仍然知之甚少。在本研究中，我们旨在描述反映全身自我运动经验的大脑网络。我们使用先前经历过的事件的检索，这已知涉及用于感知这些事件的模态的皮质代表。因此，自我运动经验的回忆可能会涉及运动和感觉大脑区域，反映出所经历的运动的主动或被动性质，但也可能涉及处理自我运动的常见大脑区域。我们进一步比较了自我和观察运动的检索网络：尽管已经表明实际的动作观察会招募与心理模拟期间活跃的大脑网络相似的网络，但尚不清楚这些经验的回忆网络在多大程度上重叠。使用 fMRI 在心理模拟（1）经历线性全身运动（主动运动和被动运输）和（2）观察另一个人执行相同任务的最近事件期间记录大脑激活模式。在经验阶段之后，参与者在 MR 会议期间回忆起这些事件。我们发现，主要的感觉运动大脑区域主导主动行走的回忆网络的组成，而回忆被动运输则招募更高水平的联想区域。两种自我运动条件都共同激活了内侧颞叶。自我体验和观察到的运动的回忆在运动计划区域重叠。我们的结果提供了证据，表明内侧颞叶对于检索自我运动信息特别重要，并且动作观察期间的运动编码反映在回忆网络中。
