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唐氏综合征患者乳牙釉质的再矿化

Remineralization of primary tooth enamel from individuals with Down syndrome.

作者信息

Okamoto Takuma, Shibata Munenori, Tsuboi Shinji, Nakagaki Haruo, Fukuta Osamu, Kusabe Yoshitaka, Inukai Junko

机构信息

School of Dentistry, Aichi-Gakuin university, Nagoya, Japan.

出版信息

J Dent Child (Chic). 2011 Jan-Apr;78(1):43-8.

PMID:22041008
Abstract

PURPOSE

The purpose of this study was to clarify the characteristics of primary tooth enamel of Down syndrome patients (DSPs). We examined 9 primary teeth of Down syndrome children and 11 primary teeth of normally developed children to investigate the remineralization processes of enamel by transverse microradiography and X ray micro analyzer (XMA).

METHODS

Mineral loss, lesion depth, maximum mineral value, minimum mineral value, depth of maximum mineral value, and depth of minimum mineral value were used to analyze transverse microradiography (TMR). In addition, we calculated the percentage of enamel remineralization.

RESULTS

All the parameters in the 2 groups showed marked recovery. The results indicated that the Down syndrome group was significantly remineralized the same way as the control group. According to the comparison of mineral content distribution by XMA, the content distribution of magnesium was different between the 2 groups.

CONCLUSION

While recovery through remineralization of primary teeth was similar between Down syndrome children and normally developed children, the mechanism of remineralization process may be different between the 2 groups; consequently, magnesium may be considered as one of the factors affecting recovery.

摘要

目的

本研究旨在阐明唐氏综合征患者(DSPs)乳牙釉质的特征。我们检查了9颗唐氏综合征儿童的乳牙和11颗正常发育儿童的乳牙,通过横向显微放射摄影术和X射线微分析仪(XMA)研究釉质的再矿化过程。

方法

使用矿物质流失、病变深度、最大矿物质值、最小矿物质值、最大矿物质值深度和最小矿物质值深度来分析横向显微放射摄影术(TMR)。此外,我们计算了釉质再矿化的百分比。

结果

两组中的所有参数均显示出明显的恢复。结果表明,唐氏综合征组与对照组以相同方式显著再矿化。根据XMA对矿物质含量分布的比较,两组之间镁的含量分布不同。

结论

虽然唐氏综合征儿童和正常发育儿童乳牙通过再矿化的恢复情况相似,但两组之间再矿化过程的机制可能不同;因此,镁可被视为影响恢复的因素之一。

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