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结直肠癌手术中强化康复方案的系统评价

A systematic review of enhanced recovery protocols in colorectal surgery.

作者信息

Rawlinson A, Kang P, Evans J, Khanna A

机构信息

Department of Surgery, Northampton General Hospital, Northampton, UK.

出版信息

Ann R Coll Surg Engl. 2011 Nov;93(8):583-8. doi: 10.1308/147870811X605219.

Abstract

INTRODUCTION

Colorectal surgery has been associated with a complication rate of 15-20% and mean post-operative inpatient stays of 6-11 days. The principles of enhanced recovery after surgery (ERAS) are well established and have been developed to optimise peri-operative care and facilitate discharge. The purpose of this systematic review is to present an updated review of peri-operative care in colorectal surgery from the available evidence and ERAS group recommendations.

METHODS

Systematic searches of the PubMed and Embase™ databases and the Cochrane library were conducted. A hand search of bibliographies of identified studies was conducted to identify any additional articles missed by the initial search strategy.

RESULTS

A total of 59 relevant studies were identified. These included six randomised controlled trials and seven clinical controlled trials that fulfilled the inclusion criteria. These studies showed reductions in duration of inpatient stays in the ERAS groups compared with more traditional care as well as reductions in morbidity and mortality rates.

CONCLUSIONS

Reviewing the data reveals that ERAS protocols have a role in reducing post-operative morbidity and result in an accelerated recovery following colorectal surgery. Similarly, both primary and overall hospital stays are reduced significantly. However, the available evidence suggests that ERAS protocols do not reduce hospital readmissions or mortality. These findings help to confirm that ERAS protocols should now be implemented as the standard approach for peri-operative care in colorectal surgery.

摘要

引言

结直肠手术的并发症发生率为15%-20%,术后平均住院时间为6-11天。术后加速康复(ERAS)原则已得到充分确立,其目的是优化围手术期护理并促进出院。本系统评价的目的是根据现有证据和ERAS小组的建议,对结直肠手术围手术期护理进行更新综述。

方法

对PubMed和Embase™数据库以及Cochrane图书馆进行系统检索。对已识别研究的参考文献进行手工检索,以识别初始检索策略遗漏的任何其他文章。

结果

共识别出59项相关研究。其中包括6项随机对照试验和7项符合纳入标准的临床对照试验。这些研究表明,与更传统的护理相比,ERAS组的住院时间缩短,发病率和死亡率也有所降低。

结论

回顾数据发现,ERAS方案在降低术后发病率和促进结直肠手术后的加速康复方面发挥了作用。同样,初次住院和总住院时间均显著缩短。然而,现有证据表明,ERAS方案并不能降低医院再入院率或死亡率。这些发现有助于证实,ERAS方案现在应作为结直肠手术围手术期护理的标准方法实施。

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