Oróstegui-Pinilla D, Rodríguez-Morales A J
Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Santander, Colombia.
Trop Biomed. 2011 Aug;28(2):339-42.
Congenital malaria is a condition rarely diagnosed, even in endemic countries. This tropical disease is associated with high mortality in the absence of timely recognition and prompt therapy, particularly when is due to Plasmodium falciparum, however Plasmodium vivax can also lead to relevant morbidity and mortality. We report an unusual case of a 19- day-old male newborn with neonatal vivax malaria, suspected primarily on the basis of positive maternal history, which presented with low birth weight, thrombocytopenia and a significant parasitemia. He responded satisfactorily to chloroquine antimalarial therapy, being successfully discharged 10 days after admission. Blood smears remained negative during the first 2 months of follow up. At 8 weeks of follow-up, she showed remarkable weight gain and was developing normally with age-appropriate anthropometry with no subsequent complications.
先天性疟疾是一种即使在疟疾流行国家也很少被诊断出来的病症。这种热带疾病如果没有得到及时识别和迅速治疗,会导致高死亡率,尤其是由恶性疟原虫引起时,不过间日疟原虫也会导致相关的发病和死亡。我们报告了一例不寻常的病例,一名19日龄的男婴患有新生儿间日疟,主要根据母亲的阳性病史怀疑此病,该男婴出生体重低、血小板减少且有明显的寄生虫血症。他对氯喹抗疟治疗反应良好,入院10天后成功出院。在随访的前两个月,血涂片一直呈阴性。在随访8周时,他体重显著增加,生长发育正常,各项人体测量指标与年龄相符,且无后续并发症。