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危地马拉低流行区先天性疟原虫疟疾:在消除疟疾背景下对临床和流行病学监测的影响。

Plasmodium vivax congenital malaria in an area of very low endemicity in Guatemala: implications for clinical and epidemiological surveillance in a malaria elimination context.

机构信息

Centro de Estudios en Salud, Universidad del Valle de Guatemala, 18 avenida 11-95 zona 15 Vista Hermosa 3, Guatemala, Guatemala.

出版信息

Malar J. 2012 Dec 8;11:411. doi: 10.1186/1475-2875-11-411.

Abstract

This is a report of the first Plasmodium vivax congenital malaria case in Guatemala and the first case in Latin America with genotypical, histological and clinical characterization. The findings show that maternal P. vivax infection still occurs in areas that are in the pathway towards malaria elimination, and can be associated with detrimental health effects for the neonate. It also highlights the need in very low transmission areas of not only maintaining, but increasing awareness of the problem and developing surveillance strategies, based on population risk, to detect the infection especially in this vulnerable group of the population.

摘要

这是首例发生在危地马拉的先天性疟疾病例报告,也是拉丁美洲首例具有基因、组织学和临床特征的病例。研究结果表明,在疟疾消除的过渡地区,母体间日疟原虫感染仍有发生,并且可能对新生儿健康产生不良影响。这也强调了在低传播地区不仅要维持,而且要加强对该问题的认识,并根据人群风险制定监测策略,以发现感染,尤其是在这一弱势群体中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9405/3541160/c29f0afbc48e/1475-2875-11-411-1.jpg

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