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[耶尔森菌所致关节炎:发病机制、诊断与治疗的新知识]

[Yersinia-induced arthritis: new knowledge of pathogenesis, diagnosis and therapy].

作者信息

Hammer M, Heesemann J, Zeidler H

机构信息

Abteilung für Rheumatologie, Medizinische Hochschule Hannover, BRD.

出版信息

Wien Med Wochenschr. 1990 Jun 30;140(12):306-11.

PMID:2204212
Abstract

Yersinia infections have been identified in rising incidence as the cause of acute or subacute intestinal or extraintestinal diseases in the past two decades. Immunopathological manifestations of Yersinia infections, e.g. Yersinia-induced arthritis, have evoked special interest among clinicians and microbiologists. Beneath epidemiological and clinical characteristics this review focuses on recent progress in pathogenesis and serological and immunohistological diagnosis of Yersiniosis. Possible consequences for newly therapeutical approaches in chronic Yersinia-induced arthritis and spondarthritis were discussed.

摘要

在过去二十年中,耶尔森菌感染作为急性或亚急性肠道或肠外疾病的病因,其发病率一直在上升。耶尔森菌感染的免疫病理表现,如耶尔森菌诱导的关节炎,引起了临床医生和微生物学家的特别关注。除了流行病学和临床特征外,本综述重点关注耶尔森菌病发病机制以及血清学和免疫组织学诊断方面的最新进展。还讨论了慢性耶尔森菌诱导的关节炎和脊椎关节炎新治疗方法可能产生的后果。

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