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阿曼肺炎链球菌的血清型流行情况及对青霉素的敏感性

Serotype Prevalence and Penicillin-susceptibility of Streptococcus pneumoniae in Oman.

作者信息

Al-Yaqoubi Mubarak M, Elhag Kamal M

出版信息

Oman Med J. 2011 Jan;26(1):43-7. doi: 10.5001/omj.2011.11.

DOI:10.5001/omj.2011.11
PMID:22043379
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3191612/
Abstract

OBJECTIVES

to determine the prevalent serotypes of Streptococcus pneumoniae and the rate of penicillin-nonsusceptibility among pneumococci in Oman.

METHODS

Pneumococcal isolates encountered during the period of September 2002 to December 2007 in the Royal Hospital were serotyped. Clinical information as well as the penicillin susceptibility reports were retrieved from the hospital information system and medical records.

RESULTS

120 strains of Streptococcus pneumoniae were isolated of which 85 strains were seroptyped. 20 different serotypes were identified, the most common seroptypes were 9A, 6B, 19F, 14 and 23F. 56% of the strains were not susceptible to pencillin, while 99% of these were susceptible to ceftriaxone. 74.3% and 46.1% of the serotypes are covered by the pneumococcal polysaccharide vaccine and the 7-valent pneumococcal conjugate vaccine respectively.

CONCLUSION

Certain few pneumococcal serotypes such as 9A, 6B and 19F are more prevalent in the Omani community than others. More than half of S. pneumoniae are not susceptible to penicillin while the great majority of the strains are susceptible to ceftriaxone.

摘要

目的

确定阿曼肺炎链球菌的流行血清型以及肺炎球菌对青霉素不敏感的比率。

方法

对2002年9月至2007年12月期间在皇家医院分离出的肺炎球菌菌株进行血清分型。从医院信息系统和病历中获取临床信息以及青霉素敏感性报告。

结果

分离出120株肺炎链球菌,其中85株进行了血清分型。鉴定出20种不同的血清型,最常见的血清型为9A、6B、19F、14和23F。56%的菌株对青霉素不敏感,而其中99%对头孢曲松敏感。分别有74.3%和46.1%的血清型可被肺炎球菌多糖疫苗和7价肺炎球菌结合疫苗覆盖。

结论

某些肺炎球菌血清型,如9A、6B和19F,在阿曼社区比其他血清型更为流行。超过一半的肺炎链球菌对青霉素不敏感,而绝大多数菌株对头孢曲松敏感。

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