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尼日利亚尼日尔州比达一所高等院校的麻疹:患病率、免疫状况及死亡模式

Measles in a tertiary institution in bida, niger state, Nigeria: prevalence, immunization status and mortality pattern.

作者信息

Adeboye Muhammed, Adesiyun Omotayo, Adegboye Abdulrasheed, Eze Edith, Abubakar Usman, Ahmed Grace, Usman Abdullahi, Amos Solomon, Rotimi Bf

出版信息

Oman Med J. 2011 Mar;26(2):114-7. doi: 10.5001/omj.2011.28.

DOI:10.5001/omj.2011.28
PMID:22043396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3191671/
Abstract

OBJECTIVES

Measles is a highly infectious immunizable disease with potential for eradication but is still responsible for high mortality among children, particularly in developing nations like Nigeria. This study aims to determine the hospital based prevalence of measles, describe the vaccination status of children managed for measles at the Federal Medical Centre, Bida, Niger state and to identify the parental disposition to measles vaccination.

METHODS

This is a cross-sectional study carried out over a period of 18 months beginning from July 2007. All children with a diagnosis of measles made clinically and reinforced with serological test in the WHO Measles, Rubella and Yellow Fever laboratory in Maitama District Hospital, Abuja were recruited. Informed consent was obtained from the parents/care givers. Structured questionnaire was used to obtain information and data analysis was by SPSS version 15.

RESULTS

One hundred and nine children were managed for measles, constituting 8% of total admission over the study period. The male to female ratio was 1.2:1. Of the 109 children with measles, 90 (82%) did not receive measles vaccination. Eighty-eight (80%) of the parents or guardian felt vaccination was bad for various reasons. Of the 23 (21.1%) children whose parents or guardians were positively disposed to vaccination, one death was recorded while the remaining seven deaths were recorded among children whose parents were negatively disposed to vaccination. All the deaths were in the non-vaccinated group below 2 years of age.

CONCLUSION

Measles is still a major health burden in our community. The majority of affected children were not vaccinated due to negative parental disposition. Continuous health education is required for change the disposition of the parents/guardian and improve vaccination coverage to minimize measles associated morbidity and mortality.

摘要

目的

麻疹是一种具有高度传染性的可免疫疾病,有根除的潜力,但仍导致儿童高死亡率,尤其是在尼日利亚等发展中国家。本研究旨在确定以医院为基础的麻疹患病率,描述尼日尔州比达联邦医疗中心接受麻疹治疗的儿童的疫苗接种状况,并确定家长对麻疹疫苗接种的态度。

方法

这是一项横断面研究,从2007年7月开始,为期18个月。招募了所有临床诊断为麻疹并在阿布贾迈塔马区医院的世卫组织麻疹、风疹和黄热病实验室通过血清学检测得到确诊的儿童。获得了家长/照顾者的知情同意。使用结构化问卷获取信息,数据分析采用SPSS 15版。

结果

109名儿童接受了麻疹治疗,占研究期间总入院人数的8%。男女比例为1.2:1。在109名麻疹患儿中,90名(82%)未接种麻疹疫苗。88名(80%)家长或监护人因各种原因认为接种疫苗有害。在23名(21.1%)家长或监护人积极倾向于接种疫苗的儿童中,有1例死亡,而其余7例死亡记录在家长消极倾向于接种疫苗的儿童中。所有死亡病例均在2岁以下未接种疫苗的儿童组中。

结论

麻疹仍然是我们社区的主要健康负担。由于家长态度消极,大多数受影响的儿童未接种疫苗。需要持续开展健康教育,以改变家长/监护人的态度,提高疫苗接种覆盖率,将与麻疹相关的发病率和死亡率降至最低。