Brewer C
Stapleford Centre, Belgravia, London.
Br J Psychiatry. 1990 Jul;157:34-40. doi: 10.1192/bjp.157.1.34.
Supervised administration of disulfiram is one of the very few treatments that can significantly reduce alcohol consumption, yet it is rarely used, despite being simple and cheap. Disulfiram is not 'aversion therapy', but a technique for facilitating exposure and response prevention, and it fits comfortably into a behavioural, social-learning model of addiction (or dependence) and its treatment. The availability of other effective antagonists, notably to opiates, suggests that an approach that is demonstrably effective in alcohol dependence may be helpful in treating other addictions. The reasons for the unpopularity of this approach appear to be largely ideological.
双硫仑的监督管理是极少数能显著减少酒精摄入量的治疗方法之一,然而尽管它简单且便宜,却很少被使用。双硫仑并非“厌恶疗法”,而是一种促进暴露和反应预防的技术,它很契合成瘾(或依赖)及其治疗的行为、社会学习模型。其他有效拮抗剂的出现,尤其是针对阿片类药物的拮抗剂,表明一种在酒精依赖治疗中已被证明有效的方法可能有助于治疗其他成瘾问题。这种方法不受欢迎的原因似乎主要是意识形态方面的。