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非裔美国人心房扑动消融术后心房颤动的发生率

Incidence of Atrial Fibrillation in African Americans post Atrial Flutter Ablation.

作者信息

L Percell Robert, Helm Robert, Monahan Kevin

机构信息

Electrophysiology Department, Bryan Heart Institute, 1600 S 48th Street, Lincoln, NE 68506, Lincoln, NE 68506.

Boston Medical Arrhythmia Center, 830 Harrison Avenue, Moakley Building, 3rd floor, Suite 3500, Boston, MA 02118.

出版信息

J Atr Fibrillation. 2020 Feb 28;12(5):2254. doi: 10.4022/jafib.2254. eCollection 2020 Feb-Mar.

Abstract

BACKGROUND

African Americans have a lower incidence of atrial arrhythmias both atrial fibrillation (AF) and atrial flutter (AFL) despite having a greater number of traditional risk factors. The incidence of atrial fibrillation after cavotricuspid isthmus (CTI) ablation in patients with typical AFL is markedly increased approaching 40% in some studies. It is unknown if African Americans specifically have a similar rate of increased AF after CTI ablation for typical AFL.We sought to identify differences in development of AF after CTI ablation for typical AFL with regards to race, between African American and non- African Americans. The hypothesis is that African Americans will have a lower incidence of AF after CTI ablation for typical AFL.

METHODS

The electronic medical records of first time, successful CTI ablations performed for typical (AFL) were retrospectively reviewed over a 48 month period. Clinical variables were retrieved from the EMR. AFL was documented on ECG, Holter/ event monitor or device interrogation at clinical follow up visits. Follow up was obtained over a 1 year period. Patients were self-identified as African American, White, Hispanic or Other.

RESULTS

The records of a total of 201 patients - 51 African Americans (25.4%) and 150 non-African Americans (74.6%) - who underwent CTI ablation for typical AFL were examined. Average age was similar (67.8 vs 66.3, p=NS) with a preponderance of men (77.6% vs 23.5%). There was a significantly lower rate of development of AF post CTI ablation for typical AFL in African Americans vs non-African Americans (22.2% vs 46.6%, p=0.002). Additionally, women were more likely to develop AF (53.1% vs 36.2%, p=0.026). African American men were the least likely to develop AF post AFL ablation (p=0.0062).

CONCLUSIONS

We observed a significantly lower incidence of AF among African American patients after CTI ablation for typical AFL.

摘要

背景

非裔美国人患房性心律失常(包括心房颤动(AF)和心房扑动(AFL))的发生率较低,尽管他们有更多的传统风险因素。在一些研究中,典型AFL患者在三尖瓣峡部(CTI)消融术后心房颤动的发生率显著增加,接近40%。尚不清楚非裔美国人在典型AFL的CTI消融术后发生AF的增加率是否有类似情况。我们试图确定在典型AFL的CTI消融术后,非裔美国人和非非裔美国人在AF发生方面的种族差异。假设是非裔美国人在典型AFL的CTI消融术后发生AF的发生率较低。

方法

回顾性分析48个月期间首次成功进行典型(AFL)CTI消融的电子病历。从电子病历中获取临床变量。在临床随访时通过心电图、动态心电图/事件监测器或设备问询记录AFL。随访1年。患者自我认定为非裔美国人、白人、西班牙裔或其他。

结果

共检查了201例接受典型AFL的CTI消融的患者记录,其中51例(25.4%)是非裔美国人,150例(74.6%)是非非裔美国人。平均年龄相似(67.8岁对66.3岁,p=无显著差异),男性占多数(77.6%对23.5%)。与非非裔美国人相比,非裔美国人在典型AFL的CTI消融术后发生AF的发生率显著较低(22.2%对46.6%,p=0.002)。此外,女性更易发生AF(53.1%对36.2%,p=0.026)。非裔美国男性在AFL消融术后发生AF的可能性最小(p=0.0062)。

结论

我们观察到非裔美国患者在典型AFL的CTI消融术后发生AF的发生率显著较低。

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