Thomas Vibha, Dobson Robin, Mennel Robert
Departments of Oncology (Thomas and Mennel) and Pathology (Dobson), Baylor Charles A. Sammons Cancer Center and Baylor University Medical Center at Dallas. Dr. Thomas is now in private practice in Denver, Colorado.
Proc (Bayl Univ Med Cent). 2011 Oct;24(4):350-3. doi: 10.1080/08998280.2011.11928757.
Primary cutaneous large B-cell lymphoma, leg type, is a rare and aggressive neoplasm as defined by the recently updated World Health Organization-European Organization for Research and Treatment of Cancer classification of cutaneous lymphomas. We present a case of a 74-year-old woman who presented with a cutaneous lesion on her forearm. Skin biopsy revealed pathology consistent with this entity. The patient was treated with systemic chemotherapy with rituximab combined with doxorubicin, cyclophosphamide, vincristine, and prednisone. Here, we review the available literature and summarize clinical features and management of this uncommon subtype of non-Hodgkin lymphoma.
原发性皮肤大B细胞淋巴瘤，腿部型，是一种罕见且侵袭性的肿瘤，这是根据世界卫生组织-欧洲癌症研究与治疗组织最近更新的皮肤淋巴瘤分类所定义的。我们报告一例74岁女性患者，其前臂出现皮肤病变。皮肤活检显示病理结果与该疾病相符。该患者接受了利妥昔单抗联合阿霉素、环磷酰胺、长春新碱和泼尼松的全身化疗。在此，我们回顾现有文献并总结这种非霍奇金淋巴瘤罕见亚型的临床特征及治疗方法。
