Pollard M, Luckert P H
Lab Anim Sci. 1979 Feb;29(1):74-7.
Liver tumors, ranging from benign nodules to carcinomas, developed spontaneously in 115 (87%) of 132 germfree Wistar rats beyond the age of 30 months. In addition, the rats developed a high incidence of benign adenomas of endocrine glands and of the breasts.
132只30月龄以上的无菌Wistar大鼠中有115只(87%)自发出现了从良性结节到癌的肝脏肿瘤。此外,这些大鼠内分泌腺和乳腺的良性腺瘤发病率很高。