Grimprel Emmanuel
Hôpital Trousseau, 26, avenue du Docteur Arnold Netter, 75012 Paris.
Bull Acad Natl Med. 2010 Nov;194(8):1451-62; discussion 1462-4.
The important burden of rotavirus infections in infants largely justifies vaccine prevention. Two attenuated oral vaccines were licensed in Europe in 2006 and have proven effective against severe rotavirus gastroenteritis in infants, yet few countries have implemented vaccination. This hesitation may be related to a very low risk of intussusception in vaccinees, but is mainly due to national differences in cost-effectiveness.
轮状病毒感染给婴儿带来的重大负担在很大程度上证明了疫苗预防的合理性。2006年，两种减毒口服疫苗在欧洲获得许可，已被证明对预防婴儿严重轮状病毒肠胃炎有效，但很少有国家实施疫苗接种。这种犹豫可能与疫苗接种者患肠套叠的风险极低有关，但主要是由于各国在成本效益方面存在差异。
