Mureşan Iulia, Picos Alina, Grad Simona, Dumitrascu D L
University of Medicine and Pharmacy Iuliu Hatieganu Cluj-Napoca, Romania, 2nd Medical Dept.
Rev Med Chir Soc Med Nat Iasi. 2011 Jul-Sep;115(3):662-71.
The pathological gastroesophageal reflux disease may lead to the gastroesophageal reflux disease (GERD), manifested as a spectrum of conditions including erosive esophagitis, Barrett esophagus and has been linked to the development of adenocarcinoma of the esophagus. The gastroesophageal reflux has been incriminated in the occurence of a number of pulmonary symptoms and diseases, otolaryngologic symptoms, and other extraesophageal manifestations. Clinicians must be aware of the possibility of some extraesophageal reflux-related manifestations, even in the absence of heartburn and acid reflux, classic esophageal symptoms of GERD. Although the correlation between gastroesophageal reflux disease and the extraesophageal manifestations has been established, a cause-and-effect relationship has not been proved yet. In this article, we present the respiratory manifestations of gastroesophageal reflux disease, referring to epidemiology, pathogenesis, diagnosis and treatment.
病理性胃食管反流病可能导致胃食管反流病（GERD），表现为一系列病症，包括糜烂性食管炎、巴雷特食管，并且与食管腺癌的发生有关。胃食管反流已被认为与多种肺部症状和疾病、耳鼻喉科症状以及其他食管外表现的发生有关。临床医生必须意识到即使没有烧心和反酸等GERD典型的食管症状，也存在一些食管外反流相关表现的可能性。尽管胃食管反流病与食管外表现之间的相关性已经确立，但因果关系尚未得到证实。在本文中，我们介绍胃食管反流病的呼吸道表现，涉及流行病学、发病机制、诊断和治疗。
