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[在一项关于吡拉西坦的双盲研究中酗酒者的认知功能]

[Cognitive function in alcoholics in a double-blind study of piracetam].

作者信息

Buranji I, Skocilić Z, Kozarić-Kovacić D

机构信息

Klinicki psiholog, Klinicka psihijatrijska bolnica Vrapce, Zagreb, Bolnicka.

出版信息

Lijec Vjesn. 1990 Mar-Apr;112(3-4):111-4.

PMID:2204773
Abstract

The effects of piracetam on cognitive functions have been studied in alcoholic patients. The investigation was carried out on 27 alcoholics who were admitted to hospital with acute withdrawal syndrome. The trial was performed under double-blind condition. Thirteen patients were treated with piracetam and 14 with placebo. The performance of patients treated with piracetam (experimental group) was significantly better at the Block-Design retest, as compared with the control subjects. This was associated with comparatively good perceptual organization, visual motor coordination and abstract reasoning in these patients. Similar kind of performance of these patients has been achieved in the tests used to measure psychomotor speed and attention capacity. Our findings agree well with some observations of the clinicians and may stimulate further research in this field.

摘要

已对酒精性患者中吡拉西坦对认知功能的影响进行了研究。对27名因急性戒断综合征入院的酗酒者进行了调查。试验在双盲条件下进行。13名患者接受吡拉西坦治疗,14名患者接受安慰剂治疗。与对照组相比,接受吡拉西坦治疗的患者(实验组)在方块设计复测中的表现明显更好。这与这些患者相对良好的知觉组织、视觉运动协调和抽象推理有关。在用于测量精神运动速度和注意力容量的测试中,这些患者也取得了类似的表现。我们的研究结果与临床医生的一些观察结果非常吻合,可能会激发该领域的进一步研究。

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