Discipline of Vascular Surgery, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
J Vasc Surg. 2012 Jan;55(1):154-6. doi: 10.1016/j.jvs.2011.07.097. Epub 2011 Nov 1.
Current data do not provide enough information on how quality of life (QoL) evolves over time in cases of endoscopic thoracic sympathectomy (ETS). The purpose of this study was to ascertain whether the immediate improvement in QoL after the surgery was sustained until the fifth postoperative year.
This was a prospective, nonrandomized and uncontrolled study. From March 2001 to December 2003, 475 consecutive patients with hyperhidrosis submitted to ETS were included. A QoL questionnaire was applied at the preoperative day, around the 30th postoperative day, and after the fifth year.
After excluding 22 patients who did not answer all the questions, we analyzed 453 patients. Their ages ranged from 11 to 57 years old, with a mean of 25.3 + 7.9 years, including 297 female patients (65.6%). All patients were assessed on three occasions: before surgery, around the 30th postoperative day, and after the fifth postoperative year. The QoL before surgery was considered to be poor or very poor for all patients. The QoL around 30 days after surgery was better in 412 patients (90.9%), the same in 27 patients (6.0%), and worse in 14 patients (3.1%). After 5 years, 409 patients (90.3%) were better, 27 (6.0%) were the same, and 14 (3.1%) were worse. There were no differences between these postoperative times according to the McNemar statistical test.
The patients had an immediate improvement in QoL after ETS, and this improvement was sustained until the fifth postoperative year.
目前的资料尚不能充分说明胸腔镜胸交感神经切断术（ETS）后患者的生活质量（QoL）随时间的变化情况。本研究旨在确定手术后 QoL 的即刻改善是否能持续到术后第 5 年。
这是一项前瞻性、非随机和非对照研究。2001 年 3 月至 2003 年 12 月，我们共纳入 475 例多汗症患者，均接受 ETS 治疗。在术前、术后 30 天左右以及术后第 5 年，我们应用 QoL 问卷进行调查。
排除未回答所有问题的 22 例患者后，我们共分析了 453 例患者。他们的年龄为 11-57 岁，平均 25.3 ± 7.9 岁，包括 297 例女性（65.6%）。所有患者均在 3 个时间点进行评估：术前、术后 30 天左右以及术后第 5 年。所有患者术前 QoL 被认为较差或极差。412 例（90.9%）患者术后 30 天 QoL 改善，27 例（6.0%）相同，14 例（3.1%）变差。术后 5 年，409 例（90.3%）患者 QoL 改善，27 例（6.0%）相同，14 例（3.1%）变差。McNemar 统计检验显示这些术后时间点之间 QoL 无差异。
ETS 后患者的 QoL 即刻改善，这种改善可持续至术后第 5 年。
