Gurnett A, Dulski P, Hsu J, Turner M J
Merck, Sharp & Dohme Research Laboratories, Rahway, NJ 07065.
Mol Biochem Parasitol. 1990 Jun;41(2):177-85. doi: 10.1016/0166-6851(90)90180-t.
A number of proteins in Eimeria tenella are shown to possess a carbohydrate similar to that found on the carboxyl terminus of the variant surface glycoprotein from Trypanosoma brucei. In trypanosomes, this carbohydrate is part of a glycolipid structure responsible for membrane attachment. In common with the variant surface glycoprotein and with other glycolipid linked proteins, the E. tenella proteins were shown to be hydrophobic. Treatment with a crude lipase preparation from T. brucei modifies these proteins to a water-soluble form.
已证明柔嫩艾美耳球虫中的一些蛋白质具有一种碳水化合物,该碳水化合物类似于在布氏锥虫变异表面糖蛋白羧基末端发现的碳水化合物。在锥虫中,这种碳水化合物是负责膜附着的糖脂结构的一部分。与变异表面糖蛋白和其他糖脂连接蛋白一样,柔嫩艾美耳球虫的蛋白质被证明具有疏水性。用来自布氏锥虫的粗脂肪酶制剂处理可将这些蛋白质转化为水溶性形式。