He Qing-xin, Li Xue-de
No. 181 Hospital of the Chinese People's Liberation Army, Guilin, Guangxi 541002, China.
Zhonghua Nan Ke Xue. 2011 Oct;17(10):939-42.
Chronic prostatitis (CP) is a common disease in men, and its pathogenesis remains to be clarified. The precise regulation of cytokines is involved in all types and all stages of CP. The interaction of inflammation, inflammatory cells and cytokines leads to the development and progression of CP. With further understanding of the immunological and molecular biological mechanisms of the disease and more inflammatory cytokines used in its detection, it is of special significance to apply cytokines in the classification and treatment of CP. This review outlines the roles of cytokines in the pathogenesis of CP, particularly chronic pelvic pain syndrome (CPPS), their relationship with CP, and their significance in the classification and diagnosis of CP/CPPS.
慢性前列腺炎（CP）是男性的常见疾病，其发病机制仍有待阐明。细胞因子的精确调控参与了CP的所有类型和所有阶段。炎症、炎症细胞和细胞因子之间的相互作用导致了CP的发生和发展。随着对该疾病免疫和分子生物学机制的进一步了解以及更多用于其检测的炎症细胞因子的出现，将细胞因子应用于CP的分类和治疗具有特殊意义。本文综述了细胞因子在CP尤其是慢性盆腔疼痛综合征（CPPS）发病机制中的作用、它们与CP的关系以及它们在CP/CPPS分类和诊断中的意义。
