Department of Surgery, Division of Urology, Mubarak Al-Kabir Hospital, Ministry of Health, Hawally, Kuwait.
J Endourol. 2012 May;26(5):535-9. doi: 10.1089/end.2011.0314. Epub 2011 Nov 21.
To assess the effect of stone location and burden on the outcome of extracorporeal shockwave lithotripsy (SWL) as a primary treatment of solitary renal stone.
The study included 438 patients with a solitary renal stone who underwent SWL as a primary treatment for their stones. All were evaluated by plain radiography of the kidneys, ureters, and bladder (KUB), ultrasonography, intravenous urography, or noncontrast enhanced CT before SWL and followed up for 3 months after treatment by KUB radiography and/or ultrasonography. Patients were classified into four groups according to stone location (renal pelvis, lower, middle, and upper calix) and three groups according to stone burden (≤ 1 cm(2), 1.1-2 cm(2), and >2 cm(2)). Treatment outcome was considered successful if no residual fragments (stone free) or clinically insignificant nonobstructing residuals less than 4 mm remained after 3 months of follow-up.
The mean age of the patients was 45.1 ± 12.5 years. The mean stone burden, number of sessions, and shockwaves for the whole study were 1.3 ± 0.49 cm(2), 2.1 ± 0.7 sessions, and 5616.6 ± 2017.4 shockwaves, respectively. The stone-free rate of the study was 65.1%. The stone-free rates of the stones in the renal pelvis, lower, middle, and upper calices were 72.4%, 56%, 55.6%, and 69%, respectively. The stone-free rate of the stones ≤ 1 cm(2), 1.1 to 2 cm(2), and >2 cm(2) was 50.2%, 39.6%, and 10.2%, respectively (P<0.05).
Stone burden rather than stone location is considered as a predicting factor for the outcome of SWL in a solitary renal stone, especially in the renal pelvis and lower calix.
评估结石位置和负荷对体外冲击波碎石术(SWL)作为单一肾结石主要治疗方法的疗效。
本研究纳入 438 例接受 SWL 作为单一肾结石主要治疗方法的患者。所有患者在 SWL 前均行肾脏、输尿管和膀胱(KUB)平片、超声、静脉尿路造影或非增强 CT 检查,并在治疗后 3 个月行 KUB 射线照相术和/或超声检查进行随访。根据结石位置(肾盂、下盏、中盏和上盏)将患者分为 4 组,根据结石负荷(≤1cm²、1.1-2cm²和>2cm²)分为 3 组。如果在 3 个月的随访后没有残留碎片(结石无残留)或残留 4mm 以下的临床意义不大的非阻塞性碎片,则认为治疗结果为成功。
患者的平均年龄为 45.1±12.5 岁。整个研究的平均结石负荷、治疗次数和冲击波数分别为 1.3±0.49cm²、2.1±0.7 次和 5616.6±2017.4 次冲击波。研究的结石清除率为 65.1%。肾盂、下盏、中盏和上盏的结石清除率分别为 72.4%、56%、55.6%和 69%。结石负荷≤1cm²、1.1-2cm²和>2cm²的结石清除率分别为 50.2%、39.6%和 10.2%(P<0.05)。
结石负荷而非结石位置被认为是 SWL 治疗单一肾结石结局的预测因素,特别是在肾盂和下盏。