National Service for Severe Tracheal Disease in Children, The Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.
Ann Thorac Surg. 2011 Nov;92(5):1870-4. doi: 10.1016/j.athoracsur.2011.07.042. Epub 2011 Oct 31.
We here report our experience with biodegradable polydioxanone stents for tracheal narrowing in children.
Eleven custom-made polydioxanone stents were implanted in 4 patients with airway narrowing due to external compression or intrinsic collapse. The median stent diameter was 9 mm (range, 6 to 14 mm) and median length was 15 mm (range, 13 to 70 mm).
Narrowing was relieved initially in all cases. There was no bleeding or perforation after polydioxanone stent implantation. Size mismatching was a problem in 2 cases. Three patients needed repeat stenting after stent absorption. There was 1 death, unrelated to the stent implantation. All 3 survivors are in good clinical condition up to 12 months after first stenting.
This pilot study shows that polydioxanone stents offer an alternative to metallic or silastic stents for collapse or external compression of the trachea in children. They may avoid the need for permanent stenting and allow subsequent growth of the airway.
我们在此报告我们使用可生物降解的聚二氧六环酮支架治疗儿童气管狭窄的经验。
4 名因外部压迫或内在塌陷导致气道狭窄的患者植入了 11 个定制的聚二氧六环酮支架。支架的平均直径为 9 毫米（范围 6 至 14 毫米），平均长度为 15 毫米（范围 13 至 70 毫米）。
所有病例最初均缓解了狭窄。聚二氧六环酮支架植入后无出血或穿孔。有 2 例存在尺寸不匹配的问题。3 例患者在支架吸收后需要再次支架置入。有 1 例死亡，与支架植入无关。所有 3 例存活者在首次支架置入后 12 个月的临床状况良好。
这项初步研究表明，对于儿童气管塌陷或外部压迫，聚二氧六环酮支架是金属或硅酮支架的替代选择。它们可以避免永久性支架的需要，并允许气道的后续生长。
