Manchester Heart Centre, Manchester Royal Infirmary, Manchester, United Kingdom.
EuroIntervention. 2012 Jun 20;8(2):267-74. doi: 10.4244/EIJV8I2A41.
Modern drug-eluting stents are constructed with thin struts and are easy to deliver and highly conformable. However, although innovative designs have enabled maintenance of radial strength, longitudinal strength may be lower with these stents and there have been recent reports of longitudinal stent compression of ostially deployed stents. We report the experience in our centre on longitudinal stent deformation and explore mechanisms of this complication and its frequency with various drug-eluting stent platforms.
Nine cases of longitudinal stent deformation were identified over a four year period representing 0.2% of cases and affected 0.097% of stents deployed. There were several mechanisms for this complication including compression by post-dilatation balloons, guide catheter extensions and proximal embolic protection devices. The rate of stent deformation varied from 0% in several stent types to 0.86% in the case of the Promus Element stent. There was one case of late stent thrombosis attributable to longitudinal stent deformation.
Longitudinal stent deformation can occur secondary to a variety of mechanisms and identification is important as, left untreated, it may be associated with a risk of stent thrombosis. Although seen with several different stents, in our series it was more commonly observed with the Promus Element stent.
现代药物洗脱支架采用较薄的支架，易于输送，高度顺应性好。然而，尽管创新设计能够维持径向强度，但这些支架的纵向强度可能较低，并且最近有报道称近端放置的支架发生纵向支架压缩。我们报告了我们中心在纵向支架变形方面的经验，并探讨了这种并发症的机制及其在各种药物洗脱支架平台中的发生频率。
在四年期间，发现了 9 例纵向支架变形病例，占病例的 0.2%，受影响的支架占 0.097%。这种并发症的发生机制有多种，包括后扩张球囊、导引导管延伸部和近端栓塞保护装置的压迫。支架变形的发生率从几种支架类型的 0%到 Promus Element 支架的 0.86%不等。有 1 例支架内晚期血栓形成归因于纵向支架变形。
纵向支架变形可能由多种机制引起，因此识别很重要，因为如果不治疗，可能会增加支架内血栓形成的风险。尽管在几种不同的支架中都观察到了这种情况，但在我们的系列中，Promus Element 支架更常见。
