Tironi C, Fruttero R, Garrone A
Dipartimento di Scienza e Tecnologia del Farmaco, Torino, Italy.
Farmaco. 1990 Apr;45(4):473-8.
Synthesis and structural characterization of 3 sulfanilamido-1-phenylpyrazoles bearing on 1-phenyl group nitro substituent o-, m-, p-positioned are reported. All derivatives are analysed through 1H and 13C NMR spectroscopy. The MIC values obtained against Escherichia coli are briefly discussed in terms of structure-activity relationship.
报道了在1-苯基上带有邻位、间位、对位硝基取代基的3-磺胺氨基-1-苯基吡唑的合成及其结构表征。所有衍生物均通过1H和13C核磁共振光谱进行分析。根据构效关系简要讨论了对大肠杆菌的最低抑菌浓度（MIC）值。
