Ghasri Pedram, Roehmholdt Brian F, Young Lorraine C
University of California, Irvine School of Medicine, Irvine, CA, USA.
J Drugs Dermatol. 2011 Sep;10(9):1067-9.
Lichen planus (LP) is an inflammatory dermatosis of unknown etiology that is primarily associated with liver disease. Recently, there have been several reports of LP developing after administration of the hepatitis B, influenza and combined MMR-DTaP-IPV vaccines. Here we report the first case of LP developing on the lower extremities of an otherwise healthy adult male after administration of the Tdap vaccine. We present this case to draw awareness to this observation in light of recently updated Tdap vaccination recommendations.
扁平苔藓(LP)是一种病因不明的炎症性皮肤病,主要与肝脏疾病相关。最近,有几篇关于在接种乙肝、流感以及联合的MMR-DTaP-IPV疫苗后发生扁平苔藓的报道。在此,我们报告首例在一名原本健康的成年男性接种破伤风、白喉、无细胞百日咳(Tdap)疫苗后下肢出现扁平苔藓的病例。鉴于最近更新的Tdap疫苗接种建议,我们展示此病例以引起对这一现象的关注。