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碘过量导致的对比剂诱发的甲状腺功能亢进。

Contrast induced hyperthyroidism due to iodine excess.

作者信息

Mushtaq Usman, Price Timothy, Laddipeerla Narsing, Townsend Amanda, Broadbridge Vy

机构信息

The Queen Elizabeth Hospital, Medicine, 28-Woodville Road, Woodville South, Adelaide, South Australia, 5011, Australia.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.1982. Epub 2009 Nov 4.

DOI:10.1136/bcr.06.2009.1982
PMID:22053166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3028253/
Abstract

Iodine induced hyperthyroidism is a thyrotoxic condition caused by exposure to excessive iodine. Historically this type of hyperthyroidism has been described in areas of iodine deficiency. With advances in medicine, iodine induced hyperthyroidism has been observed following the use of drugs containing iodine-for example, amiodarone, and contrast agents used in radiological imaging. In elderly patients it is frequently difficult to diagnose and control contrast related hyperthyroidism, as most of these patients do not always present with typical signs and symptoms of hyperthyroidism. Treatment can be very challenging as drugs commonly used to treat hyperthyroidism have little effect on already formed thyroid hormone due to iodine excess.

摘要

碘致甲状腺功能亢进症是一种因接触过量碘而引起的甲状腺毒症。从历史上看,这种类型的甲状腺功能亢进症曾在碘缺乏地区被描述过。随着医学的进步,在使用含碘药物(如胺碘酮)以及放射成像中使用的造影剂后,也观察到了碘致甲状腺功能亢进症。在老年患者中,与造影剂相关的甲状腺功能亢进症常常难以诊断和控制,因为这些患者大多并不总是表现出典型的甲状腺功能亢进症体征和症状。由于碘过量,常用于治疗甲状腺功能亢进症的药物对已形成的甲状腺激素几乎没有作用,因此治疗可能极具挑战性。

相似文献

1
Contrast induced hyperthyroidism due to iodine excess.碘过量导致的对比剂诱发的甲状腺功能亢进。
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.1982. Epub 2009 Nov 4.
2
Iodine excess and hyperthyroidism.碘过量与甲状腺功能亢进症。
Thyroid. 2001 May;11(5):493-500. doi: 10.1089/105072501300176453.
3
[Risk of hyperthyroidism in examinations with contrast media].
Aktuelle Radiol. 1996 Sep;6(5):243-8.
4
Five patients with iodine-induced hyperthyroidism.
Am J Med. 1984 Aug;77(2):378-84. doi: 10.1016/0002-9343(84)90726-5.
5
Iodine-induced hyperthyroidism as combination of different etiologies: an overlooked entity in the elderly.碘致甲状腺功能亢进症作为不同病因的组合:老年人中一个被忽视的实体。
Aging Clin Exp Res. 2016 Oct;28(5):1023-7. doi: 10.1007/s40520-015-0483-4. Epub 2015 Nov 4.
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Effects of Adequate Iodine Supply on the Incidence of Iodine-Induced Thyroid Disorders in Slovenia.充足碘供应对斯洛文尼亚碘致甲状腺疾病发病率的影响。
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Amiodarone-induced thyroid dysfunction in cardiac patients from areas with iodine deficiency.碘缺乏地区心脏病患者中胺碘酮诱发的甲状腺功能障碍
Rom J Intern Med. 2004;42(3):595-605.
8
[Iodine-induced hyperthyroidism in urology caused by using roentgen contrast media. Risks and prevention].
Urologe A. 1993 Jul;32(4):300-7.
9
[Iodine excess induced thyroid dysfunction].碘过量所致甲状腺功能异常
Rev Med Suisse. 2016 Apr 20;12(515):804-9.
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Effect of excess iodine intake on thyroid on human health.碘摄入过量对人体甲状腺及健康的影响。
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2
2021 European Thyroid Association Guidelines for the Management of Iodine-Based Contrast Media-Induced Thyroid Dysfunction.2021年欧洲甲状腺协会关于碘对比剂所致甲状腺功能障碍管理的指南。
Eur Thyroid J. 2021 Jul;10(4):269-284. doi: 10.1159/000517175. Epub 2021 Jun 16.
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A review: Radiographic iodinated contrast media-induced thyroid dysfunction.综述:放射学碘化造影剂诱发的甲状腺功能障碍
J Clin Endocrinol Metab. 2015 Feb;100(2):376-83. doi: 10.1210/jc.2014-3292. Epub 2014 Nov 6.
4
Iodide transport: implications for health and disease.碘转运:对健康与疾病的影响。
Int J Pediatr Endocrinol. 2014;2014(1):8. doi: 10.1186/1687-9856-2014-8. Epub 2014 May 30.

本文引用的文献

1
Recent developments in hyperthyroidism.甲状腺功能亢进症的最新进展
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2
Plasma inorganic iodide as a homeostatic regulator of thyroid function.血浆无机碘作为甲状腺功能的稳态调节因子。
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The effects of lithium therapy on thyroid and thyrotropin-releasing hormone.锂盐治疗对甲状腺及促甲状腺激素释放激素的影响。
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