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碘过量导致的对比剂诱发的甲状腺功能亢进。

Contrast induced hyperthyroidism due to iodine excess.

作者信息

Mushtaq Usman, Price Timothy, Laddipeerla Narsing, Townsend Amanda, Broadbridge Vy

机构信息

The Queen Elizabeth Hospital, Medicine, 28-Woodville Road, Woodville South, Adelaide, South Australia, 5011, Australia.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.1982. Epub 2009 Nov 4.

Abstract

Iodine induced hyperthyroidism is a thyrotoxic condition caused by exposure to excessive iodine. Historically this type of hyperthyroidism has been described in areas of iodine deficiency. With advances in medicine, iodine induced hyperthyroidism has been observed following the use of drugs containing iodine-for example, amiodarone, and contrast agents used in radiological imaging. In elderly patients it is frequently difficult to diagnose and control contrast related hyperthyroidism, as most of these patients do not always present with typical signs and symptoms of hyperthyroidism. Treatment can be very challenging as drugs commonly used to treat hyperthyroidism have little effect on already formed thyroid hormone due to iodine excess.

摘要

碘致甲状腺功能亢进症是一种因接触过量碘而引起的甲状腺毒症。从历史上看,这种类型的甲状腺功能亢进症曾在碘缺乏地区被描述过。随着医学的进步,在使用含碘药物(如胺碘酮)以及放射成像中使用的造影剂后,也观察到了碘致甲状腺功能亢进症。在老年患者中,与造影剂相关的甲状腺功能亢进症常常难以诊断和控制,因为这些患者大多并不总是表现出典型的甲状腺功能亢进症体征和症状。由于碘过量,常用于治疗甲状腺功能亢进症的药物对已形成的甲状腺激素几乎没有作用,因此治疗可能极具挑战性。

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本文引用的文献

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Recent developments in hyperthyroidism.甲状腺功能亢进症的最新进展
Lancet. 2009 Jun 6;373(9679):1930-2. doi: 10.1016/S0140-6736(09)61047-3.
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Lithium treatment in amiodarone-induced thyrotoxicosis.锂治疗胺碘酮所致甲状腺毒症。
Am J Med. 1997 May;102(5):454-8. doi: 10.1016/S0002-9343(97)00047-8.

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