Kim Se-Kwon, Vo Thanh-Sang, Ngo Dai-Hung
Department of Chemistry, Pukyong National University, Busan, Republic of Korea.
Adv Food Nutr Res. 2011;64:245-54. doi: 10.1016/B978-0-12-387669-0.00019-3.
Viral diseases, caused by pathogenic virus infections, are still the leading cause of death in humans worldwide. Although many antiviral agents have been developed and are used for treatment of infectious diseases, emergence of drug resistance, side effects, and the necessity for extensive clinical use are the main reasons for failure of antiviral therapy. Therefore, the development of new antiviral agents with diverse kinds of antiviral actions is required. The search for new antiviral agents focuses on not only synthetic compounds but also natural products such as plants, insects, animal organs, and their components. Recently, a great deal of interest has been expressed regarding marine algae as potential antiviral agents. This contribution focuses on antiherpes virus therapeutic agents derived from marine algae which are considered as novel functional ingredients in antiherpes virus therapy.
由致病性病毒感染引起的病毒性疾病仍然是全球人类死亡的主要原因。尽管已经开发了许多抗病毒药物并用于治疗传染病,但耐药性的出现、副作用以及广泛临床使用的必要性是抗病毒治疗失败的主要原因。因此,需要开发具有多种抗病毒作用的新型抗病毒药物。寻找新型抗病毒药物不仅集中在合成化合物上,还包括植物、昆虫、动物器官及其成分等天然产物。最近,人们对海藻作为潜在的抗病毒药物表现出了极大的兴趣。本论文着重探讨来源于海藻的抗疱疹病毒治疗药物,这些药物被认为是抗疱疹病毒治疗中的新型功能成分。