Venkatesan Jayachandran, Kim Se-Kwon
Department of Chemistry, Pukyong National University, Busan, Republic of Korea.
Adv Food Nutr Res. 2011;64:417-27. doi: 10.1016/B978-0-12-387669-0.00032-6.
Osteoporosis is one of the most common bone diseases that occur due to imbalance during bone formation and bone resorption. About half of all women over the age of 50 will have a fracture on the hip, wrist, or vertebra. Research and treatment of osteoporosis are challenging for researchers and physicians. There are several types of treatments for osteoporosis including most famous bisphosphonates, estrogen agonists/antagonists, parathyroid hormone, estrogen therapy, hormone therapy, and recently developed RANKL inhibition. In the recent days, much attention has been paid for marine algal extracts and compounds for osteoporosis treatment. In this chapter, we extensively deal with marine algae compounds and their rich mineral constituents for osteoporosis treatment.
骨质疏松症是由于骨形成和骨吸收失衡而发生的最常见的骨病之一。所有50岁以上的女性中约有一半会发生髋部、腕部或椎骨骨折。骨质疏松症的研究和治疗对研究人员和医生来说具有挑战性。骨质疏松症有几种治疗方法，包括最著名的双膦酸盐、雌激素激动剂/拮抗剂、甲状旁腺激素、雌激素疗法、激素疗法以及最近开发的RANKL抑制疗法。近年来，人们对用于治疗骨质疏松症的海藻提取物和化合物给予了极大关注。在本章中，我们将广泛探讨用于治疗骨质疏松症的海藻化合物及其丰富的矿物质成分。
