Martinazzi M, Zappalà G, Cavalleri M, Consolaro A
Minerva Med. 1979 Mar 30;70(15):1023-31.
One hundred-ninety nine cases of testicular tumours, of which 189 (94,9%) germ cell tumours, have been studied by histological methods. Seminoma with its two subtypes (anaplastic and spermatocytic) is the most frequent tumour (110 cases i.e. 55,2%), followed by embryonal carcinoma (30 cases: 15,3%), teratocarcinoma (25 cases: 13,2%), teratoma (12 cases: 6,3%) and choriocarcinoma (5 cases: 2,6%). Tumours showing more than one histologic pattern are frequent. The distinctive histologic features have studied, with emphasis of those useful for diagnostic and prognostic purposes. The ages mostly involved by various tumours are stressed. The rarest tumours are briefly described. Histologic data suggest that germinal tumours are originated by the same primordial germ cell which is able to develop various degrees of differentiation. Histologic and histogenetic features of limphomas and tumours of specialized gonadal stroma are also discussed.
对199例睾丸肿瘤进行了组织学研究,其中189例(94.9%)为生殖细胞肿瘤。精原细胞瘤及其两种亚型(间变性和精母细胞性)是最常见的肿瘤(110例,占55.2%),其次是胚胎癌(30例,占15.3%)、畸胎癌(25例,占13.2%)、畸胎瘤(12例,占6.3%)和绒毛膜癌(5例,占2.6%)。出现不止一种组织学模式的肿瘤很常见。研究了其独特的组织学特征,重点是那些对诊断和预后有帮助的特征。强调了各种肿瘤最常累及的年龄。对最罕见的肿瘤进行了简要描述。组织学数据表明,生殖细胞肿瘤起源于同一个能够发展出不同分化程度的原始生殖细胞。还讨论了淋巴瘤和特殊性腺间质肿瘤的组织学和组织发生学特征。