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瑞典北部的糖尿病:根据抗糖尿病药物处方评估患病率。

Diabetes mellitus in north Sweden: prevalence assessed from prescriptions for anti-diabetic agents.

作者信息

Forrest R D

机构信息

Department of Clinical Chemistry, Centrallasarettet, Boden, Sweden.

出版信息

J Intern Med. 1990 Sep;228(3):267-73. doi: 10.1111/j.1365-2796.1990.tb00230.x.

Abstract

A prescription inventory was performed over a period of 3 months in all pharmacies in Sweden's northernmost province. Norrbotten, in order to assess the prevalence of diabetes treated with insulin and oral anti-diabetic agents. A total of 4869 prescriptions were collected from 3482 individuals, of whom 1746 (50.1%) were men. The prevalence of drug-treated diabetes was thus 13.27/1000 inhabitants (95% confidence interval (CI) 12.8-13.7) in the province. Nearly half (47.9%) of all drug-treated diabetics were treated with insulin and the majority (74%) were over 55 years of age, with only 449 (13%) being less than 40 years old. The prevalence of diabetes was highest in individuals aged 75-84 years; in this age group it was 55.47/1000 (95% CI 50.9-58.7). There was considerable regional variation in the prevalence of diabetes in Norrbotten, with a mean prevalence of 23.84/1000 (95% CI 22.1-25.6) in the municipalities in the Torneå Valley, compared to 13.08/1000 (95% CI 1.19-1.28) for the remainder of Norrbotten. While there was no difference in the prevalence of drug-treated diabetes between men and women in the province as a whole, a slightly higher prevalence was found in women (27.41 vs. 24.73/1000) in the Torneå Valley. The prevalence of diabetes mellitus in individuals over 40 years of age was 36.62/1000 (95% CI 3.73-4.36) in The Torneå Valley, 24.38/1000 (95% CI 22.8-24.7) in the remainder of Norrbotten, and 27.88/1000 (95% CI 2.50-2.68) in the province as a whole. The estimated prevalence of diabetes mellitus in Norrbotten, including patients treated by diet alone, was of the order of 20.21/1000, with a prevalence of 40.00/1000 in subjects over the age of 40 years. Thus the prevalence of diabetes appears to be higher in the Torneå Valley than in the rest of Norrbotten, while it is apparently lower than has been reported in North Finland.

摘要

在瑞典最北部省份北博滕的所有药房进行了为期3个月的处方盘点,以评估接受胰岛素和口服抗糖尿病药物治疗的糖尿病患病率。共从3482名个体中收集到4869份处方,其中1746人(50.1%)为男性。该省药物治疗糖尿病的患病率为13.27/1000居民(95%置信区间(CI)12.8 - 13.7)。所有接受药物治疗的糖尿病患者中近一半(47.9%)接受胰岛素治疗,大多数(74%)年龄超过55岁,只有449人(13%)年龄小于40岁。糖尿病患病率在75 - 84岁个体中最高;在这个年龄组中为55.47/1000(95% CI 50.9 - 58.7)。北博滕糖尿病患病率存在显著的地区差异,托尔尼奥河谷各市镇的平均患病率为23.8,4/1000(95% CI 22.1 - 25.6),而北博滕其他地区为13.08/1000(95% CI 1.19 - 1.28)。虽然该省总体上男性和女性药物治疗糖尿病的患病率没有差异,但在托尔尼奥河谷女性患病率略高(27.41对24.73/1000)。40岁以上个体中糖尿病患病率在托尔尼奥河谷为36.62/1000(95% CI 3.73 - 4.36),北博滕其他地区为24.38/1000(95% CI 22.8 - 24.7),全省为27.88/1000(95% CI 2.50 - 2.68)。北博滕糖尿病的估计患病率,包括仅通过饮食治疗的患者,约为20.21/1000,40岁以上人群患病率为40.00/1000。因此,糖尿病患病率在托尔尼奥河谷似乎高于北博滕其他地区,而明显低于芬兰北部此前报道的患病率。

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