Jansson S P O, Fall K, Brus O, Magnuson A, Wändell P, Östgren C J, Rolandsson O
Family Medicine Research Centre, Örebro County Council, School of Health and Medical Sciences, Örebro University, Örebro, Sweden.
Clinical Epidemiology and Biostatistics, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Diabet Med. 2015 Oct;32(10):1319-28. doi: 10.1111/dme.12716. Epub 2015 Feb 20.
To investigate the changes in prevalence and incidence of pharmacologically and non-pharmacologically treated diabetes in Sweden during 2005 to 2013.
We obtained data on gender, date of birth and pharmacologically and non-pharmacologically treated diabetes from national registers for all Swedish residents.
During the study period a total of 240 871 new cases of pharmacologically treated diabetes was found. The age-standardized incidence during the follow-up was 4.34 and 3.16 per 1000 individuals in men and women, respectively. A decreasing time trend in incidence for men of 0.6% per year (0.994, 95% CI 0.989-0.999) and for women of 0.7% per year (0.993, 95% CI 0.986-0.999) was observed. The age-standardized prevalence increased from 41.9 and 29.9 per 1000 in 2005/2006 to 50.8 and 34.6 in 2012/2013 in men and women, respectively. This corresponds to an annually increasing time trend for both men (1.024, 95% CI 1.022-1.027) and women (1.019, 95% CI 1.016-1.021). The total age-standardized prevalence of pharmacologically and non-pharmacologically treated diabetes (2012) was 46.9 per 1000 (55.6 for men and 38.8 for women). This corresponds to an annually increasing time trend (2010-2012) for both men (1.017, 95% CI 1.013-1.021) and women (1.012, 95% CI 1.008-1.016).
The prevalence of pharmacologically treated diabetes increased moderately during 8 years of follow-up, while the incidence decreased modestly. This is in contrast to the results reported by most other studies. The total prevalence of diabetes (both pharmacologically and non-pharmacologically treated) in Sweden is relatively low, from a global viewpoint.
调查2005年至2013年瑞典药物治疗和非药物治疗糖尿病的患病率和发病率变化情况。
我们从瑞典所有居民的国家登记册中获取了性别、出生日期以及药物治疗和非药物治疗糖尿病的数据。
在研究期间,共发现240871例药物治疗糖尿病新病例。随访期间,男性和女性的年龄标准化发病率分别为每1000人4.34例和3.16例。观察到男性发病率每年下降0.6%(0.994,95%置信区间0.989 - 0.999),女性发病率每年下降0.7%(0.993,95%置信区间0.986 - 0.999)。年龄标准化患病率在男性中从2005/2006年的每1000人41.9例增加到2012/2013年的50.8例,在女性中从每1000人29.9例增加到34.6例。这对应于男性(1.024,95%置信区间1.022 - 1.027)和女性(1.019,95%置信区间1.016 - 1.021)每年上升的时间趋势。药物治疗和非药物治疗糖尿病的总年龄标准化患病率(2012年)为每1000人46.9例(男性为55.6例,女性为38.8例)。这对应于男性(1.017,95%置信区间1.013 - 1.021)和女性(1.012,95%置信区间1.008 - 1.016)在2010 - 2012年每年上升的时间趋势。
在8年的随访期间,药物治疗糖尿病的患病率适度增加,而发病率略有下降。这与大多数其他研究报告的结果相反。从全球角度来看,瑞典糖尿病(包括药物治疗和非药物治疗)的总患病率相对较低。