具有丰富神经纤维网和真性菊形团的胚胎性肿瘤（ETANTR）在进展过程中形态学特征消失但关键遗传学特征保留。 - Suppr

Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with loss of morphological but retained genetic key features during progression.

作者信息

Woehrer Adelheid, Slavc Irene, Peyrl Andreas, Czech Thomas, Dorfer Christian, Prayer Daniela, Stary Susanne, Streubel Berthold, Ryzhova Marina, Korshunov Andrey, Pfister Stefan M, Haberler Christine

出版信息

Acta Neuropathol. 2011 Dec;122(6):787-90. doi: 10.1007/s00401-011-0903-2. Epub 2011 Nov 6.

DOI:10.1007/s00401-011-0903-2

PMID:22057788

Abstract

摘要

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Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with loss of morphological but retained genetic key features during progression.具有丰富神经纤维网和真性菊形团的胚胎性肿瘤（ETANTR）在进展过程中形态学特征消失但关键遗传学特征保留。

Acta Neuropathol. 2011 Dec;122(6):787-90. doi: 10.1007/s00401-011-0903-2. Epub 2011 Nov 6.

Embryonal tumor with abundant neuropil and true rosettes: morphological, immunohistochemical, ultrastructural and molecular study of a case showing features of medulloepithelioma and areas of mesenchymal and epithelial differentiation.胚胎性肿瘤，伴丰富神经毡和真性菊形团：一例具有髓上皮瘤特征和间叶及上皮分化区的形态学、免疫组织化学、超微结构和分子研究。

Neuropathology. 2010 Feb 1;30(1):84-91. doi: 10.1111/j.1440-1789.2009.01040.x. Epub 2009 Jun 25.

Embryonal tumor with abundant neuropil and true rosettes with only one structure suggestive of an ependymoblastic rosette.伴有丰富神经毡及真性菊形团的胚胎性肿瘤，仅有一种结构提示室管膜母细胞菊形团。

Pathol Int. 2014 Sep;64(9):472-7. doi: 10.1111/pin.12196. Epub 2014 Sep 3.

Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with a focal amplification at chromosome 19q13.42 locus: further evidence of two new instances in China.具有丰富神经丛和真性菊形团的胚胎性肿瘤（ETANTR），在染色体 19q13.42 位置存在局灶性扩增：中国的两个新病例证据。

Neuropathology. 2011 Dec;31(6):639-47. doi: 10.1111/j.1440-1789.2011.01215.x. Epub 2011 Apr 11.

Embryonal tumor with abundant neuropil and true rosettes in the brainstem: case report.脑干中具有丰富神经纤维网和真性菊形团的胚胎性肿瘤：病例报告

J Neurosurg Pediatr. 2015 Sep;16(3):291-5. doi: 10.3171/2015.3.PEDS14727. Epub 2015 Jun 19.

[A new entity in WHO classification of tumors of the central nervous system--embryonic tumor with abundant neuropil and true rosettes: case report and review of literature].[世界卫生组织中枢神经系统肿瘤分类中的一个新实体——富含神经纤维网和真性菊形团的胚胎性肿瘤：病例报告及文献复习]

Zh Vopr Neirokhir Im N N Burdenko. 2011;75(4):25-33; discussion 33.

The role of CD133+ cells in a recurrent embryonal tumor with abundant neuropil and true rosettes (ETANTR).CD133+ 细胞在伴有丰富神经丛和真性菊形团的复发性胚胎性肿瘤（ETANTR）中的作用。

Brain Pathol. 2014 Jan;24(1):45-51. doi: 10.1111/bpa.12079. Epub 2013 Aug 12.

Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.在一种具有丰富神经纤维和真性菊形团的儿童胚胎性肿瘤中，针对19q13.42处微小RNA簇的新型基因组扩增。

Acta Neuropathol. 2009 Apr;117(4):457-64. doi: 10.1007/s00401-008-0467-y. Epub 2008 Dec 5.

TP53, β-Catenin and c-myc/N-myc status in embryonal tumours with ependymoblastic rosettes.具有室管膜菊形团的胚胎性肿瘤中的 TP53、β-连环蛋白和 c-myc/N-myc 状态。

Neuropathol Appl Neurobiol. 2011 Jun;37(4):406-13. doi: 10.1111/j.1365-2990.2010.01151.x.

Long-term survival in a case of ETANTR with histological features of neuronal maturation after therapy.1例经治疗后具有神经元成熟组织学特征的ETANTR患者的长期生存情况。

Virchows Arch. 2015 May;466(5):603-7. doi: 10.1007/s00428-015-1736-5. Epub 2015 Feb 20.

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Integrated proteomics spotlight the proteasome as a therapeutic vulnerability in embryonal tumors with multilayered rosettes.整合蛋白质组学将蛋白酶体视为具有多层菊形团的胚胎性肿瘤中的一个治疗靶点。

Neuro Oncol. 2024 May 3;26(5):935-949. doi: 10.1093/neuonc/noad265.

Embryonal Tumors of the Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors.中枢神经系统胚胎性肿瘤伴层状菊形团和非典型畸胎瘤/横纹肌样瘤。

Adv Exp Med Biol. 2023;1405:225-252. doi: 10.1007/978-3-031-23705-8_8.

Embryonal tumors with multilayered rosettes, -altered or not elsewhere classified: Clinicopathological characteristics, prognostic factors, and outcomes of 17 children from 2018 to 2022.伴有多层菊形团的胚胎性肿瘤，其他部位未分类或分类改变：2018年至2022年17例儿童患者的临床病理特征、预后因素及结局

Front Oncol. 2022 Oct 24;12:1001959. doi: 10.3389/fonc.2022.1001959. eCollection 2022.

Beyond standard data collection - the promise and potential of BRAIN (Brain tumour Registry Australia INnovation and translation registry).超越标准数据收集 - BRAIN（澳大利亚脑肿瘤登记处创新与转化登记处）的前景与潜力。

BMC Cancer. 2022 Jun 2;22(1):604. doi: 10.1186/s12885-022-09700-3.

DNA methylation profiling as a model for discovery and precision diagnostics in neuro-oncology.DNA 甲基化分析作为神经肿瘤学中发现和精准诊断的模型。

Neuro Oncol. 2021 Nov 2;23(23 Suppl 5):S16-S29. doi: 10.1093/neuonc/noab143.

Potential Importance of Early Focal Radiotherapy Following Gross Total Resection for Long-Term Survival in Children With Embryonal Tumors With Multilayered Rosettes.对于具有多层菊形团的胚胎性肿瘤患儿，在大体全切术后早期进行局部放疗对长期生存的潜在重要性。

Front Oncol. 2020 Dec 17;10:584681. doi: 10.3389/fonc.2020.584681. eCollection 2020.

Embryonal tumor with multilayered rosettes, C19MC-altered (ETMR): a newly defined pediatric brain tumor.伴有多层菊形团的胚胎性肿瘤，C19MC改变型（ETMR）：一种新定义的儿童脑肿瘤。

Int J Clin Exp Pathol. 2019 Aug 1;12(8):3156-3163. eCollection 2019.

CT and Multimodal MR Imaging Features of Embryonal Tumors with Multilayered Rosettes in Children.儿童具有多层花环状结构的胚胎性肿瘤的 CT 和多模态 MR 成像特征。

AJNR Am J Neuroradiol. 2019 Apr;40(4):732-736. doi: 10.3174/ajnr.A6001. Epub 2019 Mar 7.

Radiation for ETMR: Literature review and case series of patients treated with proton therapy.儿童胚胎性肿瘤的放射治疗：质子治疗患者的文献综述与病例系列

Clin Transl Radiat Oncol. 2018 Nov 7;15:31-37. doi: 10.1016/j.ctro.2018.11.002. eCollection 2019 Feb.

Evaluation of the good tumor response of embryonal tumor with abundant neuropil and true rosettes (ETANTR).富含神经毡和真性菊形团的胚胎性肿瘤（ETANTR）良好肿瘤反应的评估。

J Neurooncol. 2016 Jan;126(1):99-105. doi: 10.1007/s11060-015-1938-3. Epub 2015 Sep 15.

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Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with loss of morphological but retained genetic key features during progression.

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