Kress H, Swida U
Institut für Allgemeine Genetik, Freien Universität, Berlin.
Naturwissenschaften. 1990 Jul;77(7):317-24. doi: 10.1007/BF01138385.
The primary targets of steroid hormones are genes. For the ecdysone-controlled genes of Drosophila larval glue proteins proximal and distal control elements were identified by mutagenesis and sequence comparison. Their presence is required for the correct stage- and tissue-specific expression of these genes. The supposed function of these elements is described in a working model.
类固醇激素的主要作用靶点是基因。对于果蝇幼虫黏蛋白中由蜕皮激素控制的基因,通过诱变和序列比较确定了近端和远端控制元件。这些元件的存在是这些基因正确的阶段特异性和组织特异性表达所必需的。在一个工作模型中描述了这些元件的假定功能。