Snyder Laura A, Michael Helen
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
J Am Anim Hosp Assoc. 2011 Nov-Dec;47(6):443-6. doi: 10.5326/JAAHA-MS-5693.
A 7 mo old Labrador retriever presented for evaluation of facial swelling associated with a 5 cm oral mass extending caudally from the upper third premolar on the left side. Cytology revealed an atypical population of round cells of undetermined origin. A diagnosis of alveolar rhabdomyosarcoma (RMS) was reached via histopathology and confirmed with positive immunohistochemical staining for desmin. In humans, RMSs have a well-described round cell cytologic appearance. Few descriptions of veterinary cases of RMS exist. This report describes the cytologic appearance of alveolar RMS in a young dog and both summarizes and compares findings throughout the veterinary and human literature.
一只7月龄的拉布拉多猎犬因左侧上颌第三前磨牙尾侧延伸的5厘米口腔肿物伴面部肿胀前来评估。细胞学检查显示一群来源不明的非典型圆形细胞。经组织病理学诊断为肺泡横纹肌肉瘤(RMS),并通过结蛋白免疫组化染色阳性得以证实。在人类中,RMS具有典型的圆形细胞细胞学表现。关于兽医病例中的RMS描述很少。本报告描述了一只幼犬肺泡RMS的细胞学表现,并总结和比较了兽医及人类文献中的研究结果。