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2-[5-甲基-2-(丙烷-2-基)苯氧基]-N'-{2-[5-甲基-2-(丙烷-2-基)苯氧基]乙酰基}乙酰肼

2-[5-Methyl-2-(propan-2-yl)phen-oxy]-N'-{2-[5-methyl-2-(propan-2-yl)phen-oxy]acet-yl}acetohydrazide.

作者信息

Fun Hoong-Kun, Quah Ching Kheng, Kalluraya Balakrishna

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2414. doi: 10.1107/S1600536811033964. Epub 2011 Aug 27.

DOI:10.1107/S1600536811033964
PMID:22059000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3200946/
Abstract

The complete mol-ecule of the title compound, C(24)H(32)N(2)O(4), is generated by a crystallographic inversion center. The 1,2-diethyl-hydrazine moiety is nearly planar, with a maximum deviation of 0.024 (1) Å, and is inclined at a dihedral angle of 54.20 (4)° with the phenyl ring. In the crystal, [001] chains are formed, with adjacent mol-ecules in the chain linked by pair of inter-molecular N-H⋯O hydrogen bonds, generating R(2) (2)(10) ring motifs. Inter-molecular C-H⋯O hydrogen bonds and C-H⋯π inter-actions are also observed.

摘要

标题化合物C(24)H(32)N(2)O(4)的完整分子由一个晶体学倒转中心产生。1,2 - 二乙基肼部分近乎平面，最大偏差为0.024 (1) Å，并且与苯环的二面角为54.20 (4)°。在晶体中，形成了[001]链，链中相邻分子通过一对分子间N - H⋯O氢键相连，形成R(2) (2)(10)环基序。还观察到分子间C - H⋯O氢键和C - H⋯π相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd7a/3200946/7a5842169335/e-67-o2414-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd7a/3200946/9ba97d01c955/e-67-o2414-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd7a/3200946/7a5842169335/e-67-o2414-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd7a/3200946/9ba97d01c955/e-67-o2414-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd7a/3200946/7a5842169335/e-67-o2414-fig2.jpg

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3
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Eur J Med Chem. 2008 Aug;43(8):1715-20. doi: 10.1016/j.ejmech.2007.08.002. Epub 2007 Aug 30.
4
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5
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