Rosebrough R W, Geis E G, Henderson K, Frobish L T
Poult Sci. 1978 Nov;57(6):1652-7. doi: 10.3382/ps.0571652.
An experiment was conducted with turkey hens to investigate the effect of substituting 30% of the carbohydrate calories with corn oil, 1,3-butanediol, or glycerol. Birds fed additional corn oil had the lowest liver glycogen concentration. Corn oil increased phosphorylase, a total phosphorylase, and glycogen synthetase I in comparison to the controls. Also, additional corn oil resulted in the highest specific activity of glucose-6-phosphatase. Dietary glycerol caused the highest concentration of liver glycogen. Glycerol increased glycogen synthetase I, but had little effect upon total activity in comparison to butanediol in the diet. Both butanediol and glycerol gave similar phosphorylase a activity, but butanediol increased total activity. The fat-fed and control-fed hens regulated hepatic glycogen concentration through phosphorylase, while glycerol and butanediol-fed hens regulated glycogen through glycogen synthetase. In vitro activation of glycogen synthetase I was deficient in hens fed additional corn oil, indicating a lack of glycogen synthetase phosphatase activity. The order of activation (glycerol greater than butanediol greater than control greater than corn oil) corresponds to the rank of glycogen concentrations
用母火鸡进行了一项实验，以研究用玉米油、1,3 - 丁二醇或甘油替代30%碳水化合物热量的效果。额外喂食玉米油的母鸡肝脏糖原浓度最低。与对照组相比，玉米油增加了磷酸化酶、总磷酸化酶和糖原合成酶I。此外，额外的玉米油导致葡萄糖 - 6 - 磷酸酶的比活性最高。日粮中的甘油导致肝脏糖原浓度最高。甘油增加了糖原合成酶I，但与日粮中的丁二醇相比，对总活性影响较小。丁二醇和甘油的磷酸化酶a活性相似，但丁二醇增加了总活性。喂食脂肪和对照日粮的母鸡通过磷酸化酶调节肝脏糖原浓度，而喂食甘油和丁二醇的母鸡通过糖原合成酶调节糖原。额外喂食玉米油的母鸡中糖原合成酶I的体外激活不足，表明缺乏糖原合成酶磷酸酶活性。激活顺序（甘油＞丁二醇＞对照＞玉米油）与糖原浓度的排名相对应
