Rumessen J J, Bodé S, Hamberg O, Gudmand-Høyer E
Department of Internal Medicine F, Gentofte Hospital, University of Copenhagen, Denmark.
Am J Clin Nutr. 1990 Oct;52(4):675-81. doi: 10.1093/ajcn/52.4.675.
Fructans are naturally occurring plant oligosaccharides with sweetening properties. Fructans (FAs) isolated from Jerusalem artichokes (Helianthus tuberosus) were studied with respect to intestinal handling and influence on blood glucose (BG), insulin, and C-peptide responses in eight healthy subjects. The responses were compared with those for fructose ingestion. The effect of FAs added to a wheat-starch meal was also studied. Standardized breath-hydrogen excretion indicated that FAs were completely malabsorbed and, after a 20-g dose, traces of FA were detected in 24-h urine collections in one subject only. Orocecal transit times were longer for FAs than for lactulose and fructose. The BG and insulin increments were very low after FA ingestion, lower than after fructose ingestion, whereas hydrogen production was much higher. Areas under BG curves tended to be smaller when 10 g FA was added to a 50-g wheat-starch meal, but there was no apparent interference with starch absorption.
果聚糖是具有甜味特性的天然存在的植物寡糖。对从菊芋（Helianthus tuberosus）中分离出的果聚糖（FAs）进行了研究，观察其在8名健康受试者体内的肠道处理情况以及对血糖（BG）、胰岛素和C肽反应的影响。将这些反应与果糖摄入后的反应进行了比较。还研究了添加到小麦淀粉餐中的FAs的作用。标准化的呼气氢排泄表明FAs完全不能被吸收，在给予20克剂量后，仅在一名受试者的24小时尿液收集物中检测到微量的FA。FAs的口盲肠转运时间比乳果糖和果糖的长。摄入FA后，BG和胰岛素的增量非常低，低于摄入果糖后的增量，而氢气产生量则高得多。当在50克小麦淀粉餐中添加10克FA时，BG曲线下面积往往较小，但对淀粉吸收没有明显干扰。
