Cárdenas-Ayala V M, Sánchez-Vargas C
Departamento de Investigación, Instituto Nacional de Salud Pública, México.
Bol Med Hosp Infant Mex. 1990 Jul;47(7):500-5.
A number of issues have arisen concerning the current measles epidemic. In this paper we review: 1) the causes of this cyclic rise; 2) the benefit of a vaccination program sustained during more than 15 years; 3) the vaccine efficacy, as well as 4) the vaccination coverage goal for controlling measles. Immediate causes of the epidemic recurrence are: 1) low vaccination coverage, and 2) an increasing absolute number of newborns enlarges the pool of susceptibles. A strategy to identify now-vaccinated children in a systematic fashion is suggested. As long as measles transmission occurs even if measles vaccination coverage increases, the proportion of vaccinated cases will not decrease. Within optimal values of vaccine efficacy this proportion will increase as the coverage increases. The universal goal for measles vaccination is stressed.
关于当前的麻疹疫情，已经出现了一些问题。在本文中，我们将回顾：1）这种周期性上升的原因；2）持续超过15年的疫苗接种计划的益处；3）疫苗效力，以及4）控制麻疹的疫苗接种覆盖率目标。疫情复发的直接原因是：1）疫苗接种覆盖率低，以及2）新生儿绝对数量的增加扩大了易感人群。建议采用一种系统的方法来识别未接种疫苗的儿童。只要麻疹传播仍在发生，即使麻疹疫苗接种覆盖率有所提高，接种疫苗病例的比例也不会下降。在疫苗效力的最佳值范围内，这一比例将随着覆盖率的提高而增加。强调了麻疹疫苗接种的普遍目标。
