Radiology Department, University of Insubria, Viale Borri, 57, Varese, Italy.
Updates Surg. 2011 Dec;63(4):259-69. doi: 10.1007/s13304-011-0118-z. Epub 2011 Nov 8.
This study on the treatment of kidney tumor metastases aims to expose our experience in different interventional therapies for renal cell carcinomas metastasis in different organs, broaching their complications and comparing our results with the literature. In the last 5 years, after informed consent, 22 patients with metastatic kidney tumors were enrolled in this retrospective observational study. According to lesion sites, different interventional procedures may be performed: RFA for pancreas, lung, adrenal gland and liver lesions; TAE and RFA for bone lesions and IVC filter positioning for thrombosis of renal vein. There were mainly satisfactory results: complete necrosis of pancreas, lung and adrenal gland metastasis with a technical success rate of 100%; after TAE and RFA of bone lesions, an acceptable blood loss was registered during surgical intervention; no recurrences after liver metastasis ablation were observed in a period of 3 months; positioning of IVC filter was technically correct in 100% of patients; few complications, such as diffuse abdominal pain for pancreas, pneumothorax in the lung RCC metastasis and a post-RFA syndrome for the adrenal. There was a nodular recurrence along the ablation margin in one liver RCC metastasis. Inclusion criteria were relatively strict and only 22 patients were included in this study. The follow-up has been relatively short to date, so we are not certain of the long-term results, though these are comparable to those found in literature. It is possible to conclude that Interventional radiology plays an important role in RCC metastasis treatment, if we have few complications and improved outcomes.
这项关于肾肿瘤转移治疗的研究旨在展示我们在不同介入治疗方法治疗不同器官肾细胞癌转移方面的经验,探讨其并发症,并将我们的结果与文献进行比较。在过去的 5 年中,在获得知情同意后,我们对 22 例患有转移性肾肿瘤的患者进行了回顾性观察研究。根据病变部位的不同,可能会进行不同的介入治疗:RFA 治疗胰腺、肺、肾上腺和肝脏病变;TAE 和 RFA 治疗骨病变,IVC 滤器定位治疗肾静脉血栓形成。主要结果令人满意:胰腺、肺和肾上腺转移的完全坏死,技术成功率为 100%;骨病变行 TAE 和 RFA 后,手术干预期间记录到可接受的出血量;肝转移消融后 3 个月内未观察到复发;IVC 滤器定位的技术成功率为 100%;并发症较少,如胰腺弥散性腹痛、肺 RCC 转移性气胸和肾上腺 RFA 后综合征。在一个肝 RCC 转移灶中,沿消融边界出现结节性复发。纳入标准相对严格,本研究仅纳入 22 例患者。到目前为止,随访时间相对较短,因此我们不能确定长期结果,但这些结果与文献中的结果相当。可以得出结论,如果我们的并发症较少且治疗效果得到改善,那么介入放射学在肾细胞癌转移治疗中起着重要作用。