Haroon Mohammad, Sathiadoss Paul, Hibbert Rebecca M, Jeyaraj Satheesh Krishna, Lim Christopher, Schieda Nicola
Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Ottawa, ON, K1B 4L9, Canada.
Joint Department of Medical Imaging, University of Toronto, 585 University Avenue, Toronto, ON, M5G 2N2, Canada.
Abdom Radiol (NY). 2021 Nov;46(11):5386-5407. doi: 10.1007/s00261-021-03178-6. Epub 2021 Jul 10.
Ablative (percutaneous and stereotactic) thermal and radiotherapy procedures for management of both primary and metastatic renal cell carcinoma are increasing in popularity in clinical practice. Data suggest comparable efficacy with lower cost and morbidity compared to nephrectomy. Ablative therapies may be used alone or in conjunction with surgery or chemotherapy for treatment of primary tumor and metastatic disease. Imaging plays a crucial role in pre-treatment selection and planning of ablation, intra-procedural guidance, evaluation for complications, short- and long-term post-procedural surveillance of disease, and treatment response. Treatment response and disease recurrence may differ considerably after ablation, particularly for stereotactic radiotherapy, when compared to conventional surgical and chemotherapies. This article reviews the current and emerging role of imaging for ablative therapy of renal cell carcinoma.
用于治疗原发性和转移性肾细胞癌的消融性（经皮和立体定向）热疗和放射治疗程序在临床实践中的应用越来越广泛。数据表明，与肾切除术相比，其疗效相当，但成本和发病率更低。消融疗法可单独使用，也可与手术或化疗联合用于治疗原发性肿瘤和转移性疾病。影像学在消融治疗的术前选择和规划、术中引导、并发症评估、术后短期和长期疾病监测以及治疗反应评估中起着至关重要的作用。与传统的手术和化疗相比，消融治疗后，尤其是立体定向放射治疗后，治疗反应和疾病复发可能有很大差异。本文综述了影像学在肾细胞癌消融治疗中的当前及新兴作用。
