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2 - [(1R,3S) - 6,7 - 二甲氧基 - 1 - 苯基 - 1,2,3,4 - 四氢异喹啉 - 3 - 基] - 4 - 苯基 - 1,3 - 噻唑

2-[(1R,3S)-6,7-Dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinolin-3-yl]-4-phenyl-1,3-thia-zole.

作者信息

Pawar Sunayna, Katharigatta Venugopala, Govender Thavendran, Kruger Hendrik G, Maguire Glenn E M

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2722. doi: 10.1107/S1600536811037494. Epub 2011 Sep 30.

Abstract

In the title compound, C(26)H(24)N(2)O(2)S, the dihedral angle between the thia-zole ring and the adjacent phenyl ring is 3.02 (15)°. The N-containing six-membered ring of the tetra-hydro-isoquinoline unit adopts a half-chair conformation. The dihedral angle between the least-squares plane of the tetra-hydro-isoquinoline ring system and its nearest phenyl ring is 76.90 (13)°. No classical hydrogen bonds nor π-π inter-actions were found in the crystal structure.

摘要

在标题化合物C(26)H(24)N(2)O(2)S中,噻唑环与相邻苯环之间的二面角为3.02 (15)°。四氢异喹啉单元的含氮六元环呈半椅式构象。四氢异喹啉环系的最小二乘平面与其最近的苯环之间的二面角为76.90 (13)°。在晶体结构中未发现经典氢键和π-π相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8851/3201443/a224f6ea0099/e-67-o2722-fig1.jpg

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