• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

（S）-4-叔丁基-2-（1,2,3,4-四氢异喹啉-3-基）-1,3-噻唑

(S)-4-tert-Butyl-2-(1,2,3,4-tetra-hydro-isoquinolin-3-yl)-1,3-thia-zole.

作者信息

Pawar Sunayna, Govender Thavendran, Kruger Hendrik G, Maguire Glenn E M

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Aug 1;68(Pt 8):o2487. doi: 10.1107/S160053681203173X. Epub 2012 Jul 18.

DOI:10.1107/S160053681203173X
PMID:22904929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3414942/
Abstract

In the title compound, C(16)H(20)N(2)S, a potential tetra-hydro-isoquinoline (TIQ) thia-zole ligand, the N-containing six-membered ring of the TIQ unit adopts a half-chair conformation. There are four mol-ecules in the asymmetric unit. No classical hydrogen bonds or π-π inter-actions were found in the crystal structure.

摘要

在标题化合物C(16)H(20)N(2)S中，一种潜在的四氢异喹啉（TIQ）噻唑配体，TIQ单元中含氮的六元环呈半椅式构象。不对称单元中有四个分子。在晶体结构中未发现经典氢键或π-π相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/3414942/eff0164ce469/e-68-o2487-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/3414942/eff0164ce469/e-68-o2487-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/3414942/eff0164ce469/e-68-o2487-fig1.jpg

相似文献

1
(S)-4-tert-Butyl-2-(1,2,3,4-tetra-hydro-isoquinolin-3-yl)-1,3-thia-zole.（S）-4-叔丁基-2-（1,2,3,4-四氢异喹啉-3-基）-1,3-噻唑
Acta Crystallogr Sect E Struct Rep Online. 2012 Aug 1;68(Pt 8):o2487. doi: 10.1107/S160053681203173X. Epub 2012 Jul 18.
2
2-[(1R,3S)-6,7-Dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinolin-3-yl]-4-phenyl-1,3-thia-zole.2 - [(1R,3S) - 6,7 - 二甲氧基 - 1 - 苯基 - 1,2,3,4 - 四氢异喹啉 - 3 - 基] - 4 - 苯基 - 1,3 - 噻唑
Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2722. doi: 10.1107/S1600536811037494. Epub 2011 Sep 30.
3
(S)-4-Phenyl-2-(1,2,3,4-tetra-hydro-isoquinolin-3-yl)-1,3-thia-zole.（S）-4-苯基-2-（1,2,3,4-四氢异喹啉-3-基）-1,3-噻唑
Acta Crystallogr Sect E Struct Rep Online. 2012 Jan;68(Pt 1):o176. doi: 10.1107/S1600536811052585. Epub 2011 Dec 21.
4
4-[(2,5-Dimethyl-1,3-thia-zol-4-yl)meth-yl]-4-hydr-oxy-2-methyl-isoquinoline-1,3(2H,4H)-dione.4-[(2,5-二甲基-1,3-噻唑-4-基)甲基]-4-羟基-2-甲基异喹啉-1,3(2H,4H)-二酮
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 27;66(Pt 4):o964-5. doi: 10.1107/S1600536810011141.
5
2-Phenyl-5,6,7,8-tetra-hydro-imidazo[2,1-b][1,3]benzo-thia-zole.2-苯基-5,6,7,8-四氢-咪唑并[2,1-b][1,3]苯并噻唑
Acta Crystallogr Sect E Struct Rep Online. 2014 May 17;70(Pt 6):o668. doi: 10.1107/S1600536814010885. eCollection 2014 Jun 1.
6
7'-(Naphthalen-1-yl)-5''-[(naphthalen-2-yl)-methyl-idene]-1',3',5',6',7',7a'-hexa-hydro-dispiro-[acenaphthene-1,5'-pyrrolo-[1,2-c]thia-zole-6',3''-piperidine]-2(1H),4''-dione.7'-（萘-1-基）-5''-[(萘-2-基)-亚甲基]-1',3',5',6',7',7a'-六氢-二螺-[苊烯-1,5'-吡咯并-[1,2-c]噻唑-6',3''-哌啶]-2(1H),4''-二酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o858-9. doi: 10.1107/S1600536812007271. Epub 2012 Feb 29.
7
4-[(2,4-Dimethyl-thia-zol-5-yl)meth-yl]-4-hydr-oxy-2-methyl-isoquinoline-1,3(2H,4H)-dione.4-[(2,4-二甲基-噻唑-5-基)甲基]-4-羟基-2-甲基异喹啉-1,3(2H,4H)-二酮
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 27;66(Pt 4):o940-1. doi: 10.1107/S1600536810010469.
8
5''-(4-Meth-oxy-benzyl-idene)-7'-(4-meth-oxy-phen-yl)-1''-methyl-5',6',7',7a'-tetra-hydro-dispiro-[acenaphthene-1,5'-pyrrolo-[1,2-c][1,3]thia-zole-6',3''-piperidine]-2,4''-dione.5''-(4-甲氧基-亚苄基)-7'-(4-甲氧基-苯基)-1''-甲基-5',6',7',7a'-四氢-二螺-[苊烯-1,5'-吡咯并-[1,2-c][1,3]噻唑-6',3''-哌啶]-2,4''-二酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3210. doi: 10.1107/S1600536811045934. Epub 2011 Nov 5.
9
Crystal structure of 6-(4-chloro-phen-yl)-6a-nitro-6,6a,6b,7,9,11a-hexa-hydro-spiro[chromeno[3',4':3,4]pyrrolo-[1,2-c]thia-zole-11,11'-indeno-[1,2-b]quinoxaline] chloro-form monosolvate.6-(4-氯苯基)-6a-硝基-6,6a,6b,7,9,11a-六氢-螺[色烯并[3',4':3,4]吡咯并[1,2-c]噻唑-11,11'-茚并[1,2-b]喹喔啉]氯仿单溶剂合物的晶体结构
Acta Crystallogr Sect E Struct Rep Online. 2014 Sep 20;70(Pt 10):o1111-2. doi: 10.1107/S1600536814020601. eCollection 2014 Oct 1.
10
7'-Phenyl-5',6',7',7a'-tetra-hydro-dipiro[indan-2,5'-pyrrolo-[1,2-c][1,3]thia-zole-6',2''-indan]-1,3,1''-trione.7'-苯基-5',6',7',7a'-四氢-二吡咯并[茚满-2,5'-吡咯并[1,2-c][1,3]噻唑-6',2''-茚满]-1,3,1''-三酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3218-9. doi: 10.1107/S1600536811046174. Epub 2011 Nov 5.

本文引用的文献

1
2-[(1R,3S)-6,7-Dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinolin-3-yl]-4-phenyl-1,3-thia-zole.2 - [(1R,3S) - 6,7 - 二甲氧基 - 1 - 苯基 - 1,2,3,4 - 四氢异喹啉 - 3 - 基] - 4 - 苯基 - 1,3 - 噻唑
Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2722. doi: 10.1107/S1600536811037494. Epub 2011 Sep 30.
2
(1S,3S)-Methyl 2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carboxyl-ate.(1S,3S)-2-苄基-6,7-二甲氧基-1-苯基-1,2,3,4-四氢异喹啉-3-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1403. doi: 10.1107/S1600536811017430. Epub 2011 May 14.
3
(S)-N-Benzyl-2-methyl-1,2,3,4-tetra-hydro-isoquinoline-3-carboxamide.
(S)-N-苄基-2-甲基-1,2,3,4-四氢异喹啉-3-甲酰胺
Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 11;67(Pt 1):o67. doi: 10.1107/S1600536810050361.
4
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.