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Merkel cell carcinoma in a 17-year-old boy, report of a highly aggressive fatal case and review of the literature.

作者信息

Marzban Saeed, Geramizadeh Bita, Farzaneh Mohammad-Reza

机构信息

Department of Plastic and Reconstructive Surgery;

出版信息

Rare Tumors. 2011 Jul 11;3(3):e34. doi: 10.4081/rt.2011.e34. Epub 2011 Oct 21.

DOI:10.4081/rt.2011.e34
PMID:22066041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3208421/
Abstract

Merkel cell carcinoma is a rare tumor frequently involving the skin with an aggressive behavior and fatal outcome. It occurs mostly in the caucasian race between 60-80 years of age and it is rare in children. Herein we report our experience with a highly aggressive fatal Merkel cell carcinoma in an immunocompetent 17-year-old boy. Its characteristics and treatment modalities will be also discussed.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e9e/3208421/fb5fd03eb954/rt-2011-3-e34-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e9e/3208421/fb5fd03eb954/rt-2011-3-e34-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e9e/3208421/fb5fd03eb954/rt-2011-3-e34-g001.jpg

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本文引用的文献

1
Merkel cell carcinoma of skin-current controversies and recommendations.皮肤默克尔细胞癌——当前的争议与建议
Rare Tumors. 2011 Apr 4;3(2):e23. doi: 10.4081/rt.2011.e23.
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Merkel cell carcinoma.默克尔细胞癌。
Arch Pathol Lab Med. 2010 Nov;134(11):1711-6. doi: 10.5858/2009-0165-RSR2.1.
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Merkel cell carcinoma.默克尔细胞癌。
治疗晚期 Merkel 细胞癌：当前的治疗选择和新型免疫治疗方法。
Target Oncol. 2018 Oct;13(5):567-582. doi: 10.1007/s11523-018-0585-y.
4
Merkel cell carcinoma: Epidemiology, pathogenesis, diagnosis and therapy.默克尔细胞癌：流行病学、发病机制、诊断与治疗。
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Ann Oncol. 2010 Oct;21 Suppl 7:vii81-5. doi: 10.1093/annonc/mdq366.
4
Therapeutic options for treatment of Merkel cell carcinoma.治疗 Merkel 细胞癌的治疗选择。
Eur Arch Otorhinolaryngol. 2011 Mar;268(3):443-8. doi: 10.1007/s00405-010-1354-4. Epub 2010 Aug 27.
5
Paranuclear dots of neurofilament reliably identify Merkel cell carcinoma.
J Cutan Pathol. 2010 Aug;37(8):821-3. doi: 10.1111/j.1600-0560.2010.01567_1.x.
6
Toward better management of merkel cell carcinoma using a consensus staging system, new diagnostic codes and a recently discovered virus.借助共识分期系统、新诊断编码以及最近发现的一种病毒，实现对默克尔细胞癌的更好管理。
Actas Dermosifiliogr. 2009 Dec;100 Suppl 2(Suppl 2):49-54. doi: 10.1016/s0001-7310(09)73378-2.
7
Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study.基于3870例病例的默克尔细胞癌的人口统计学、形态学和生存率：一项基于人群的研究。
J Cutan Pathol. 2010 Jan;37(1):20-7. doi: 10.1111/j.1600-0560.2009.01370.x. Epub 2009 Jul 23.
8
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J Clin Oncol. 2009 Aug 20;27(24):4021-6. doi: 10.1200/JCO.2009.22.6605. Epub 2009 Jul 13.
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